prikaz prve stranice dokumenta Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors
  Preuzmi
PDF 1.53 MB
Znanstveni rad - Pregledni rad
Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors
Journal of Clinical Medicine, 14 (2025), 1; 190. https://doi.org/10.3390/jcm14010190
Bogović Crnčić, Tatjana; Ćurko-Cofek, Božena; Batičić, Lara; Girotto, Neva; Tomaš, Maja Ilić; Kršek, Antea; Krištofić, Ines; Štimac, Tea; Perić, Ivona; Sotošek, Vlatka; Klobučar, Sanja

Citirajte ovaj rad

Bogović Crnčić, T., Ćurko Cofek, B., Batičić, L., Girotto, N., Tomaš, M. I., Kršek, A. ... Klobučar, S. (2025). Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors. Journal of Clinical Medicine, 14. (1). doi: 10.3390/jcm14010190

Bogović Crnčić, Tatjana, et al. "Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors." Journal of Clinical Medicine, vol. 14, br. 1, 2025. https://doi.org/10.3390/jcm14010190

Bogović Crnčić, Tatjana, Božena Ćurko Cofek, Lara Batičić, Neva Girotto, Maja Ilić Tomaš, Antea Kršek, Ines Krištofić, et al. "Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors." Journal of Clinical Medicine 14, br. 1 (2025). https://doi.org/10.3390/jcm14010190

Bogović Crnčić, T., et al. (2025) 'Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors', Journal of Clinical Medicine, 14(1). doi: 10.3390/jcm14010190

Bogović Crnčić T, Ćurko Cofek B, Batičić L, Girotto N, Tomaš MI, Kršek A, i sur.. Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors. Journal of Clinical Medicine [Internet]. 01.2025. [pristupljeno 21.01.2025.];14(1). doi: 10.3390/jcm14010190

T. Bogović Crnčić, et al., "Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors", Journal of Clinical Medicine, vol. 14, br. 1, Siječanj 2025. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:508639. [Citirano: 21.01.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:508639
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)Autoimmune Thyroid Disease and Pregnancy: The Interaction Between Genetics, Epigenetics and Environmental Factors
AutorTatjana Bogović Crnčić
AutorBožena Ćurko-Cofek
AutorLara Batičić
AutorNeva Girotto
AutorMaja Ilić Tomaš
AutorAntea Kršek
AutorInes Krištofić
AutorTea Štimac
AutorIvona Perić
AutorVlatka Sotošek
AutorSanja Klobučar
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za nuklearnu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Autoimmune thyroid disease (AITD) is the leading cause of thyroid dysfunction globally, characterized primarily by two distinct clinical manifestations: Hashimoto’s thyroiditis (HT) and Graves’ disease (GD). The prevalence of AITD is approximately twice as high in women compared to men, with a particularly pronounced risk during the reproductive years. Pregnancy exerts profound effects on thyroid physiology and immune regulation due to hormonal fluctuations and immune adaptations aimed at fostering maternal–fetal tolerance, potentially triggering or exacerbating AITD. The impact of AITD on pregnancy outcomes is multifaceted. Both HT and GD have been associated with adverse obstetric and neonatal outcomes, including miscarriage, preterm delivery, preeclampsia and fetal growth restriction. Inadequately managed AITD can also affect fetal neurodevelopment due to disrupted maternal thyroid hormone availability during critical periods of brain maturation. This review explores the complex interplay between the genetic, epigenetic and environmental factors that drive AITD during pregnancy, highlighting their roles in disease development and impacts on pregnancy outcomes. Gaining a deeper understanding of these mechanisms is crucial for improving diagnostic tools, treatment options and preventive measures to enhance the health and well-being of both the mother and the newborn.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Medicine
Brojčani podacivol. 14, br. 1, 190
e-ISSN2077-0383
DOIhttps://doi.org/10.3390/jcm14010190
URN:NBNurn:nbn:hr:184:508639
Datum objave publikacije2025-01
ProjektŠifra: uniri-iskusni-biomed-23-61
Naziv (hrvatski): Dinamičke promjene stanica prirođene imunosti u trudnica s autoimunom bolesti štitne žlijezde
Naziv (engleski): Dynamic changes of innate immune cells in pregnant women with autoimmune thyroid disease
Voditelj: Tatjana Bogović Crnčić
Pravna nadležnost: Hrvatska
Financijer: Sveučilište u Rijeci
URL dokumentahttps://www.mdpi.com/2077-0383/14/1/190
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-01-10 12:02:06