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Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease
Future Pharmacology, 4 (2024), 2; 352-379. https://doi.org/10.3390/futurepharmacol4020020
Kršek, Antea; Batičić, Lara

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Kršek, A. i Batičić, L. (2024). Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease. Future Pharmacology, 4. (2), 352-379. doi: 10.3390/futurepharmacol4020020

Kršek, Antea i Lara Batičić. "Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease." Future Pharmacology, vol. 4, br. 2, 2024, str. 352-379. https://doi.org/10.3390/futurepharmacol4020020

Kršek, Antea i Lara Batičić. "Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease." Future Pharmacology 4, br. 2 (2024): 352-379. https://doi.org/10.3390/futurepharmacol4020020

Kršek, A. i Batičić, L. (2024) 'Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease', Future Pharmacology, 4(2), str. 352-379. doi: 10.3390/futurepharmacol4020020

Kršek A, Batičić L. Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease. Future Pharmacology [Internet]. 30.04.2024. [pristupljeno 05.05.2024.];4(2):352-379. doi: 10.3390/futurepharmacol4020020

A. Kršek i L. Batičić, "Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease", Future Pharmacology, vol. 4, br. 2, str. 352-379, Travanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:926704. [Citirano: 05.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:926704
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Podaci o radu
Naslov (engleski)Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease
AutorAntea Kršek
AutorLara Batičić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Medicinska biokemija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Farmakologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Neurologija
Sažetak (engleski)
Neurodegenerative disorders entail a progressive loss of neurons in cerebral and peripheral tissues, coupled with the aggregation of proteins exhibiting altered physicochemical properties. Crucial to these conditions is the gradual degradation of the central nervous system, manifesting as impairments in mobility, aberrant behaviors, and cognitive deficits. Mechanisms such as proteotoxic stress, neuroinflammation, oxidative stress, and programmed cell death contribute to the ongoing dysfunction and demise of neurons. Presently, neurodegenerative diseases lack definitive cures, and available therapies primarily offer palliative relief. The integration of nanotechnology into medical practices has significantly augmented both treatment efficacy and diagnostic capabilities. Nanoparticles, capable of traversing the blood–brain barrier, hold considerable potential for diagnosing and treating brain pathologies. By combining gene therapy with nanotechnology, the therapeutic effectiveness against neurodegenerative diseases can be substantially enhanced. Recent advancements in nano-biomaterial-based methodologies have fortified existing approaches to neural stem cell (NSC) differentiation therapies. NSC-targeting technologies offer a promising, potentially safe method for treating neurodegenerative diseases. This review endeavors to summarize current insights and perspectives on nanotechnology-driven therapeutic innovations in neurodegenerative disorders, with a particular emphasis on Alzheimer’s and Parkinson’s disease.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaFuture Pharmacology
Brojčani podacivol. 4, br. 2, str. 352-379
e-ISSN2673-9879
DOIhttps://doi.org/10.3390/futurepharmacol4020020
URN:NBNurn:nbn:hr:184:926704
Datum objave publikacije2024-04-30
URL dokumentahttps://www.mdpi.com/2673-9879/4/2/20
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-05-03 10:49:54