prikaz prve stranice dokumenta Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease
  Download
PDF 1.71 MB
Scientific paper - Review paper
Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease
Future Pharmacology, 4 (2024), 2; 352-379. https://doi.org/10.3390/futurepharmacol4020020
Kršek, Antea; Batičić, Lara

Cite this document

Kršek, A. & Batičić, L. (2024). Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease. Future Pharmacology, 4. (2), 352-379. doi: 10.3390/futurepharmacol4020020

Kršek, Antea and Lara Batičić. "Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease." Future Pharmacology, vol. 4, no. 2, 2024, pp. 352-379. https://doi.org/10.3390/futurepharmacol4020020

Kršek, Antea and Lara Batičić. "Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease." Future Pharmacology 4, no. 2 (2024): 352-379. https://doi.org/10.3390/futurepharmacol4020020

Kršek, A. and Batičić, L. (2024) 'Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease', Future Pharmacology, 4(2), pp. 352-379. doi: 10.3390/futurepharmacol4020020

Kršek A, Batičić L. Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease. Future Pharmacology [Internet]. 2024 April 30 [cited 2024 August 03];4(2):352-379. doi: 10.3390/futurepharmacol4020020

A. Kršek and L. Batičić, "Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease", Future Pharmacology, vol. 4, no. 2, pp. 352-379, April 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:926704. [Accessed: 03 August 2024]

Please login to the repository to save this object to your list.
Metadata
Title (english)Nanotechnology-Driven Therapeutic Innovations in Neurodegenerative Disorders: A Focus on Alzheimer’s and Parkinson’s Disease
AuthorAntea Kršek
AuthorLara Batičić
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Chemistry and Biochemistry)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Medical Biochemistry
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Pharmacology
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (english)
Neurodegenerative disorders entail a progressive loss of neurons in cerebral and peripheral tissues, coupled with the aggregation of proteins exhibiting altered physicochemical properties. Crucial to these conditions is the gradual degradation of the central nervous system, manifesting as impairments in mobility, aberrant behaviors, and cognitive deficits. Mechanisms such as proteotoxic stress, neuroinflammation, oxidative stress, and programmed cell death contribute to the ongoing dysfunction and demise of neurons. Presently, neurodegenerative diseases lack definitive cures, and available therapies primarily offer palliative relief. The integration of nanotechnology into medical practices has significantly augmented both treatment efficacy and diagnostic capabilities. Nanoparticles, capable of traversing the blood–brain barrier, hold considerable potential for diagnosing and treating brain pathologies. By combining gene therapy with nanotechnology, the therapeutic effectiveness against neurodegenerative diseases can be substantially enhanced. Recent advancements in nano-biomaterial-based methodologies have fortified existing approaches to neural stem cell (NSC) differentiation therapies. NSC-targeting technologies offer a promising, potentially safe method for treating neurodegenerative diseases. This review endeavors to summarize current insights and perspectives on nanotechnology-driven therapeutic innovations in neurodegenerative disorders, with a particular emphasis on Alzheimer’s and Parkinson’s disease.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleFuture Pharmacology
Numberingvol. 4, no. 2, pp. 352-379
e-ISSN2673-9879
DOIhttps://doi.org/10.3390/futurepharmacol4020020
URN:NBNurn:nbn:hr:184:926704
Publication2024-04-30
Document URLhttps://www.mdpi.com/2673-9879/4/2/20
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-05-03 10:49:54