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Master's thesis Open access

Development and Validation of a Reporter Gene Assay for the Detection of Agonists and Antagonists of the Aryl Hydrocarbon Receptor

Kramarić, Luka

2026-05-20

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor belonging to the bHLH/PAS protein family that participates in the regulation of xenobiotic metabolism, immunomodulation and maintenance of barrier tissue homeostasis in or…

University of Rijeka University of Rijeka, Faculty of Medicine Department of Pharmacology

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aril-ugljikovodični receptor FICZ CH-223191 metoda izvještajnog gena luciferaza aryl hydrocarbon receptor FICZ CH-223191 reporter gene assay luciferase

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Master's thesis Open access

DEVELOPMENT AND VALIDATION OF A REPORTER GENE ASSAY FOR THE DETECTION OF FERROPTOSIS INDUCERS AND INHIBITORS

Vujanić, Lorenzo

2026-09-06

In this study, a reporter gene assay for the assessment of ferroptosis in HT1080-HMGB1-Lucia cells was successfully validated. The aim of the study was to develop an in vitro method for testing potential inducers and inhibitors of ferroptosis and to …

University of Rijeka University of Rijeka, Faculty of Medicine Department of Pharmacology

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feroptoza metoda izvještajnog gena validacija metode induktori feroptoze inhibitori feroptoze HT1080-HMGB1-Lucia

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Master's thesis Open access

The Role of Magnetic Resonance Imaging in the Diagnosis and Monitoring of Multiple Sclerosis

Šmit, Ana

2026-09-11

Multiple sclerosis is a chronic immune-mediated disease of the central nervous system characterized by inflammatory demyelination and neurodegenerative processes. Magnetic resonance imaging (MRI) is the principal imaging modality in the diagnosis and…

University of Rijeka University of Rijeka, Faculty of Medicine

Repository of the University of Rijeka, Faculty of Medicine

lezije s paramagnetskim rubom McDonaldovi kriteriji magnetska rezonancija multipla skleroza znak središnje vene Multiple Sclerosis Magnetic Resonance Imaging McDonald Criteria Central Vein Sign Paramagnetic Rim Lesions

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Master's thesis Open access

VIŠE OD MEHANIČKOG OPTEREĆENJA: METABOLIČKA POVEZANOST PRETILOSTI I OSTEOARTRITISA KOLJENA

Mikić, Marija

2026-09-11

Knee osteoarthritis (KOA) is a highly prevalent disorder of the musculoskeletal sytstem and represents the most frequent form of arthritis. It is a leading cause of impaired mobility and functional disability, particularly among older alults. KOA aff…

University of Rijeka University of Rijeka, Faculty of Medicine

Repository of the University of Rijeka, Faculty of Medicine

osteoartritis koljena leptin pretilost adipokini metabolički sindrom knee osteoarthritis leptin obesity adipokines metabolic syndrome

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Master's thesis Open access

Prevalencija kardiovaskularnih bolesti na području grada Rijeke

Jugović, Barbara

2026-09-11

Kardiovaskularne bolesti jedan su od vodećih uzroka pobola i smrtnosti te predstavljaju značajan javnozdravstveni problem u svijetu, Europi i Republici Hrvatskoj. Njihova pojavnost povezana je s dobi, spolom, životnim navikama i prisutnošću čimbenika…

University of Rijeka University of Rijeka, Faculty of Medicine

Repository of the University of Rijeka, Faculty of Medicine

cerebrovaskularni poremećaji Hrvatska ishemija miokarda javno zdravstvo kardiovaskularne bolesti prevalencija preventivna medicina

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Master's thesis Open access

Cytogenetic analysis of chromosomal aberrations in individuals with fertility issues

Ružić, Sara Aurora

2026-09-10

Infertility represents a significant public health issue affecting an increasing number of couples of reproductive age, with genetic factors playing an important role in its etiology. Chromosomal aberrations can cause impaired gametogenesis, spontane…

University of Rijeka University of Rijeka, Faculty of Medicine Department of Biology and Medical Genetics

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citogenetička analiza kariotipizacija kromosomske aberacije neplodnost reprodukcija cytogenetic analysis karyotyping chromosomal aberrations infertility reproduction

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Dissertation Access restricted to institution's students and staff

THE ROLE OF MICRO-RIBONUCLEIC ACIDS AS BIOMARKERS IN RIGHT-SIDED AND LEFT-SIDED COLON ADENOCARCINOMA

Kršul, Dorian

2026

Objectives: To assess miR-185-5p, miR-141-5p and miR-21-5p expression in tumor versus matched adjacent mucosa in stage I-III colon cancer, evaluate tumor sidedness, and explore links with KRAS/NRAS/BRAF status. Patients and Methods: Paired FFPE tumor…

University of Rijeka University of Rijeka, Faculty of Medicine

Repository of the University of Rijeka, Faculty of Medicine

karcinom kolona mikroRNA miR-21-5p miR-141-5p miR-185-5p lateralnost mutacije colon cancer microRNA miR-21-5p miR-141-5p miR-185-5p tumor sidedness BRAF

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Master's thesis Open access

Prenatal diagnostic of Down syndrome

Borovac, Antonio

2026-09-09

Non-invasive screening methods assess the individual risk of chromosomal abnormalities in featus, with a positive result indicating the need for invasive cytogenetic prenatal diagnosis. This retrospective study aimed to determine the number of amniot…

University of Rijeka University of Rijeka, Faculty of Medicine Department of Biology and Medical Genetics

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Downov sindrom prenatalna dijagnostika amniocenteza citogenetika NIPT Down syndrome prenatal diagnosis amniocentesis cytogenetics NIPT

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Master's thesis Open access

The role of interleukin genes polymorphisms in preterm birth

Dekanić, Lucija

2025-09-10

Preterm birth is defined as any birth occurring before the 37th week of pregnancy and is the leading cause of mortality in children under the age of five. It is considered to be the result of multiple factors such as genetics, sociodemographic profil…

University of Rijeka University of Rijeka, Faculty of Medicine

Repository of the University of Rijeka, Faculty of Medicine

prijevremeni porod interelukin 6 -174G/C polimorfizam preterm birth interleukin 6 -174G/C polymorphism

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Contribution in a journal Open access

Late Oral Complications in Childhood Cancer Survivors: Implications for Pediatric Dentistry and Survivorship Care

Ružman, Lucija Zulijani, Ana Škrinjarić, Tomislav Buljan, Domagoj Stepan Giljević, Jasminka Bilić Čače, Iva Milardović, Ana

2026

Survival rates for children treated for malignant diseases continue to improve, yet many survivors face persistent late oral complications that affect function, aesthetics, and quality of life. Oncological therapy, especially at a young age a…

Clinical Center Rijeka

Children Vol. 13, Br. 1, str. 114–121

DOI10.3390/children13010114 eISSN2227-9067

Repository of the University of Rijeka, Faculty of Medicine

cancer survivors child long-term adverse effects long-term care oral health

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