prikaz prve stranice dokumenta Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report
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Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report
JBRA Assisted Reproduction, 27 (2023), 4; 747-751. https://doi.org/10.5935/1518-0557.20230027
Sušanj Šepić, Tina; Smiljan Severinski, Neda; Eminović, Senija; Radojčić Badovinac, Anđelka; Višnić, Alenka

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Sušanj Šepić, T., Smiljan Severinski, N., Eminović, S., Radojčić Badovinac, A. i Višnić, A. (2023). Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report. JBRA Assisted Reproduction, 27. (4), 747-751. doi: 10.5935/1518-0557.20230027

Sušanj Šepić, Tina, et al. "Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report." JBRA Assisted Reproduction, vol. 27, br. 4, 2023, str. 747-751. https://doi.org/10.5935/1518-0557.20230027

Sušanj Šepić, Tina, Neda Smiljan Severinski, Senija Eminović, Anđelka Radojčić Badovinac i Alenka Višnić. "Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report." JBRA Assisted Reproduction 27, br. 4 (2023): 747-751. https://doi.org/10.5935/1518-0557.20230027

Sušanj Šepić, T., et al. (2023) 'Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report', JBRA Assisted Reproduction, 27(4), str. 747-751. doi: 10.5935/1518-0557.20230027

Sušanj Šepić T, Smiljan Severinski N, Eminović S, Radojčić Badovinac A, Višnić A. Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report. JBRA Assisted Reproduction [Internet]. 2023. [pristupljeno 28.12.2024.];27(4):747-751. doi: 10.5935/1518-0557.20230027

T. Sušanj Šepić, N. Smiljan Severinski, S. Eminović, A. Radojčić Badovinac i A. Višnić, "Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report", JBRA Assisted Reproduction, vol. 27, br. 4, str. 747-751, 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:629794. [Citirano: 28.12.2024.]

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Podaci o radu
Naslov (engleski)Complete restoration of fertility in a patient treated for androgen-secreting granulosa cell tumor- Case report
AutorTina Sušanj Šepić
AutorNeda Smiljan Severinski
AutorSenija Eminović
AutorAnđelka Radojčić Badovinac
AutorAlenka Višnić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Case report: A 35-yr-old patient suffering from secondary amenorrhea for two years before she was diagnosed. Secondary amenorrhea occurred after the first normal vaginal delivery, and it was initially associated with breastfeeding and a formerly diagnosed thyroid disease. Transvaginal ultrasound confirmed a tumorous mass of the right ovary. Blood hormone tests detected high serum inhibin B and Anti-Müllerian hormone levels and high androgen level with no signs of virilization. Surgical treatment was indicated for a definitive diagnosis of suspected sex cord-stromal tumor. Right-sided laparoscopic salpingo-oophorectomy was performed, and the histopathological analysis confirmed the diagnosis of granulosa cell tumor adult type. The oncological team recommended adjuvant chemotherapy after the operation, but the patient did not give an informed consent. One month after surgical treatment, spontaneous menstrual bleeding occurred with normalization of sex hormone levels and the menstrual cycle. Nine months after surgical treatment, the patient was examined again due to secondary amenorrhea. Ultrasound confirmed a vital intrauterine pregnancy. The pregnancy course was normal, and the patient had a full-term spontaneous vaginal delivery of her second child. Conclusion: Restoration of fertility after a temporary loss due to hormone-secreting granulosa cell tumor is possible after sparing surgical treatment. The role of adjuvant chemotherapy is controversial, particularly in patients with stage I-II disease because of the rarity of this tumor and the absence of prospective randomized studies.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJBRA Assisted Reproduction
Brojčani podacivol. 27, br. 4, str. 747-751
p-ISSN1518-0557
DOIhttps://doi.org/10.5935/1518-0557.20230027
URN:NBNurn:nbn:hr:184:629794
Datum objave publikacije2023
URL dokumentahttps://www.jbra.com.br/trab/pub/download_trabalho.php?fileSource=/var/www/vhosts/jbra.com.br/media/trab/arq_4896&fileName=2397%20-%20Complete.pdf&id_trabalho=1828
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-03-22 12:23:42