prikaz prve stranice dokumenta The Role of PrPC in the Course of CMV Infection
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diplomski rad
The Role of PrPC in the Course of CMV Infection
graduation thesis
2023. urn:nbn:hr:184:624209
Herrlich, Benjamin
Sveučilište u Rijeci
Medicinski fakultet

Citirajte ovaj rad

Herrlich, B. (2023). The Role of PrPC in the Course of CMV Infection : graduation thesis (Diplomski rad). Rijeka: Sveučilište u Rijeci, Medicinski fakultet. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:624209

Herrlich, Benjamin. "The Role of PrPC in the Course of CMV Infection : graduation thesis." Diplomski rad, Sveučilište u Rijeci, Medicinski fakultet, 2023. https://urn.nsk.hr/urn:nbn:hr:184:624209

Herrlich, Benjamin. "The Role of PrPC in the Course of CMV Infection : graduation thesis." Diplomski rad, Sveučilište u Rijeci, Medicinski fakultet, 2023. https://urn.nsk.hr/urn:nbn:hr:184:624209

Herrlich, B. (2023). 'The Role of PrPC in the Course of CMV Infection : graduation thesis', Diplomski rad, Sveučilište u Rijeci, Medicinski fakultet, citirano: 21.10.2024., https://urn.nsk.hr/urn:nbn:hr:184:624209

Herrlich B. The Role of PrPC in the Course of CMV Infection : graduation thesis [Diplomski rad]. Rijeka: Sveučilište u Rijeci, Medicinski fakultet; 2023 [pristupljeno 21.10.2024.] Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:624209

B. Herrlich, "The Role of PrPC in the Course of CMV Infection : graduation thesis", Diplomski rad, Sveučilište u Rijeci, Medicinski fakultet, Rijeka, 2023. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:624209

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Podaci o radu
NaslovThe Role of PrPC in the Course of CMV Infection : graduation thesis
AutorBenjamin Herrlich
MentorTihana Lenac Roviš (mentor)
Član povjerenstvaGordana Blagojević Zagorac (predsjednik povjerenstva)
Član povjerenstvaAstrid Krmpotić (član povjerenstva)
Član povjerenstvaStipan Jonjić (član povjerenstva)
Ustanova koja je dodijelila
akademski / stručni stupanj		Sveučilište u Rijeci
Medicinski fakultet
Rijeka
Datum i država obrane2023-07-14, Hrvatska
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Citologija, histologija i embriologija
Sažetak
This thesis investigates the influence of PrPC on the immune response against MCMV in lung tissue. Histological investigations support the preliminary claim that the absence of PrPC influences viral clearance in multiple tissues such as in the liver leading to less recorded tissue insult. Further, viral titration of lung tissue demonstrated no significant difference between wild type mice and those lacking PrPC . Searching for an explanation for this finding, we analyzed differences in cytokine levels in the brain and lungs. We found IL-17A levels to behave differently in the lungs compared to brain tissue. Only in the lungs did we record a significant increase of IL-17A levels in PrPC KO mice following infection while in brain tissue a comparable finding was absent. Concisely, our findings indicate the MCMV inflicted immune response to be differently affected by the absence of PrPC in comparison to other tissues and the expression of IL-17A to be unrelated to PrPC .
Ključne riječi
Jezikengleski
URN:NBNurn:nbn:hr:184:624209
Studijski programNaziv: Medicina
Vrsta studija: sveučilišni
Stupanj studija: integrirani preddiplomski i diplomski
Akademski / stručni naziv: doktor/doktorica medicine (dr. med.)
Vrsta resursaTekst
Način izrade datotekeIzvorno digitalna
Prava pristupaOtvoreni pristup
Datum isteka embarga: 2023-07-14
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-07-11 08:53:41