prikaz prve stranice dokumenta Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report
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Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report
Croatian Medical Journal, 62 (2021), 3; 288-296. https://doi.org/10.3325/cmj.2021.62.288
Primorac, Dragan; Stojanović Stipić, Sanda; Strbad, Marko; Girandon, Lenart; Barlič, Ariana; Ivić, Ivo; Marasović Krstulović, Daniela; Jukić, Irena; Halassy, Beata; Hećimović, Ana; Matišić, Vid; Molnar, Vilim

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Primorac, D., Stojanović Stipić, S., Strbad, M., Girandon, L., Barlič, A., Ivić, I. ... Molnar, V. (2021). Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report. Croatian Medical Journal, 62. (3), 288-296. doi: 10.3325/cmj.2021.62.288

Primorac, Dragan, et al. "Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report." Croatian Medical Journal, vol. 62, br. 3, 2021, str. 288-296. https://doi.org/10.3325/cmj.2021.62.288

Primorac, Dragan, Sanda Stojanović Stipić, Marko Strbad, Lenart Girandon, Ariana Barlič, Ivo Ivić, Daniela Marasović Krstulović, et al. "Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report." Croatian Medical Journal 62, br. 3 (2021): 288-296. https://doi.org/10.3325/cmj.2021.62.288

Primorac, D., et al. (2021) 'Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report', Croatian Medical Journal, 62(3), str. 288-296. doi: 10.3325/cmj.2021.62.288

Primorac D, Stojanović Stipić S, Strbad M, Girandon L, Barlič A, Ivić I, i sur.. Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report. Croatian Medical Journal [Internet]. 2021. [pristupljeno 16.11.2024.];62(3):288-296. doi: 10.3325/cmj.2021.62.288

D. Primorac, et al., "Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report", Croatian Medical Journal, vol. 62, br. 3, str. 288-296, 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:969076. [Citirano: 16.11.2024.]

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Naslov (engleski)Compassionate mesenchymal stem cell treatment in a severe COVID-19 patient: a case report
AutorDragan Primorac
AutorSanda Stojanović Stipić
AutorMarko Strbad
AutorLenart Girandon
AutorAriana Barlič
AutorIvo Ivić
AutorDaniela Marasović Krstulović
AutorIrena Jukić
AutorBeata Halassy
AutorAna Hećimović
AutorVid Matišić
AutorVilim Molnar
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
COVID-19 presentations range from cold-like symptoms to severe symptoms with the development of acute respiratory distress syndrome (ARDS). We report on a severe COVID-19 patient who was mechanically ventilated and who developed ARDS and bacterial infection. Because of rapid clinical deterioration and the exhaustion of other treatment options, the family and attending physicians requested a compassionate use of adult allogeneic bone marrow-derived mesenchymal stem cells (MSC) in addition to commonly used immunosuppressive, antiviral, and supportive therapy. The clinical course is discussed thoroughly, with a special emphasis on the safety and effect of MSC therapy. Compassionate MSC treatment, given in three rounds, affected ARDS regression. The patient was discharged from the intensive care unit after 31 days and from hospital after 49 days in a good general condition. MSC treatment was not associated with any side effects and was well tolerated in a three-week period; therefore, it should be studied in larger trials and considered for compassionate use
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 62, br. 3, str. 288-296
p-ISSN0353-9504
e-ISSN1332-8166
DOIhttps://doi.org/10.3325/cmj.2021.62.288
URN:NBNurn:nbn:hr:184:969076
Datum objave publikacije2021
ProjektŠifra: IP-CORONA-2020-04-2053
Naziv (hrvatski): Stvaranje preduvjeta za uvođenje SARS-CoV-2 seroterapije u Hrvatskoj
Voditelj: Beata Halassy
Pravna nadležnost: Hrvatska
Financijer: HRZZ
Linija financiranja: IP-CORONA
ProjektŠifra: KK.011.1.01.0006
Naziv (hrvatski): Jačanje kapaciteta CerVirVac-a za istraživanja u virusnoj imunologiji i vakcinologiji
Voditelj: Stipan Jonjić
Pravna nadležnost: eu
Financijer: ERDF
ProjektŠifra: N/A
Naziv (hrvatski): Centar izvrsnosti za virusnu imunologiju i cjepiva
Naziv (engleski): Centre of Excellence for Research in Viral Immunology and the Development of New Vaccines
Kratica: CERVirVac
Voditelj: Stipan Jonjić
Pravna nadležnost: Hrvatska
Financijer: MZOS
Linija financiranja: ZCI
URL dokumentahttps://hrcak.srce.hr/278142
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Dijeli pod istim uvjetima 4.0 međunarodna (CC BY-SA 4.0)
Datum i vrijeme pohrane2023-02-02 07:47:41