prikaz prve stranice dokumenta Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)
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Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)
British journal of anaesthesia, 126 (2021), 6; 1157-1172. https://doi.org/10.1016/j.bja.2021.02.016.
Disma, Nicola; Veyckemans, Francis; Virag, Katalin; Butković, Diana; Kerovec Sorić, Ivana; Kralik, Sandra; Markić, Ana; AŽman, Josip; Markić, Joško; Pupačić, Daniela

Citirajte ovaj rad

Disma, N., Veyckemans, F., Virag, K., Butković, D., Kerovec Sorić, I., Kralik, S. ... Pupačić, D. (2021). Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE). British journal of anaesthesia, 126. (6), 1157-1172. doi: 10.1016/j.bja.2021.02.016.

Disma, Nicola, et al. "Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)." British journal of anaesthesia, vol. 126, br. 6, 2021, str. 1157-1172. https://doi.org/10.1016/j.bja.2021.02.016.

Disma, Nicola, Francis Veyckemans, Katalin Virag, Diana Butković, Ivana Kerovec Sorić, Sandra Kralik, Ana Markić, Josip AŽman, Joško Markić i Daniela Pupačić. "Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)." British journal of anaesthesia 126, br. 6 (2021): 1157-1172. https://doi.org/10.1016/j.bja.2021.02.016.

Disma, N., et al. (2021) 'Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)', British journal of anaesthesia, 126(6), str. 1157-1172. doi: 10.1016/j.bja.2021.02.016.

Disma N, Veyckemans F, Virag K, Butković D, Kerovec Sorić I, Kralik S, i sur.. Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE). British journal of anaesthesia [Internet]. 2021. [pristupljeno 17.11.2024.];126(6):1157-1172. doi: 10.1016/j.bja.2021.02.016.

N. Disma, et al., "Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)", British journal of anaesthesia, vol. 126, br. 6, str. 1157-1172, 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:232879. [Citirano: 17.11.2024.]

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Podaci o radu
Naslov (engleski)Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)
AutorNicola Disma
AutorFrancis Veyckemans
AutorKatalin Virag
AutorDiana Butković
AutorIvana Kerovec Sorić
AutorSandra Kralik
AutorAna Markić
AutorJosip AŽman
AutorJoško Markić
AutorDaniela Pupačić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Background Neonates and infants requiring anaesthesia are at risk of physiological instability and complications, but triggers for peri- anaesthetic interventions and associations with subsequent outcome are unknown. Methods This prospective, observational study recruited patients up to 60 weeks' postmenstrual age undergoing anaesthesia for surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 and January 2017. The primary aim was to identify thresholds of pre-determined physiological variables that triggered a medical intervention. The secondary aims were to evaluate morbidities, mortality at 30 and 90 days, or both, and associations with critical events. Results Infants (n=5609) born at mean (standard deviation [sd]) 36.2 (4.4) weeks postmenstrual age (35.7% preterm) underwent 6542 procedures within 63 (48) days of birth. Critical event(s) requiring intervention occurred in 35.2% of cases, mainly hypotension (>30% decrease in blood pressure) or reduced oxygenation (SpO2 <85%). Postmenstrual age influenced the incidence and thresholds for intervention. Risk of critical events was increased by prior neonatal medical conditions, congenital anomalies, or both (relative risk [RR]=1.16 ; 95% confidence interval [CI], 1.04– 1.28) and in those requiring preoperative intensive support (RR=1.27 ; 95% CI, 1.15– 1.41). Additional complications occurred in 16.3% of patients by 30 days, and overall 90- day mortality was 3.2% (95% CI, 2.7–3.7%). Co- occurrence of intraoperative hypotension, hypoxaemia, and anaemia was associated with increased risk of morbidity (RR=3.56 ; 95% CI, 1.64–7.71) and mortality (RR=19.80 ; 95% CI, 5.87–66.7). Conclusions Variability in physiological thresholds that triggered an intervention, and the impact of poor tissue oxygenation on patient's outcome, highlight the need for more standardised perioperative management guidelines for neonates and infants.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBritish journal of anaesthesia
Brojčani podacivol. 126, br. 6, str. 1157-1172
p-ISSN0007-0912
DOIhttps://doi.org/10.1016/j.bja.2021.02.016.
URN:NBNurn:nbn:hr:184:232879
Datum objave publikacije2021
URL dokumentahttp://bib.irb.hr/1132179
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2023-01-30 12:36:07