prikaz prve stranice dokumenta Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease
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Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease
Wiener klinische Wochenschrift, 126 (2014), 15-16; 474-479. https://doi.org/10.1007/s00508-014-0538-0
Mikolašević, Ivana; Orlic, Lidija; Milić, Sandra; Lukenda, Vesna; Rački, Sanjin; Štimac, Davor; Avdovic, Ervin; Zaputović, Luka

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Mikolašević, I., Orlic, L., Milić, S., Lukenda, V., Rački, S., Štimac, D. ... Zaputović, L. (2014). Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease. Wiener klinische Wochenschrift, 126. (15-16), 474-479. doi: 10.1007/s00508-014-0538-0

Mikolašević, Ivana, et al. "Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease." Wiener klinische Wochenschrift, vol. 126, br. 15-16, 2014, str. 474-479. https://doi.org/10.1007/s00508-014-0538-0

Mikolašević, Ivana, Lidija Orlic, Sandra Milić, Vesna Lukenda, Sanjin Rački, Davor Štimac, Ervin Avdovic i Luka Zaputović. "Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease." Wiener klinische Wochenschrift 126, br. 15-16 (2014): 474-479. https://doi.org/10.1007/s00508-014-0538-0

Mikolašević, I., et al. (2014) 'Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease', Wiener klinische Wochenschrift, 126(15-16), str. 474-479. doi: 10.1007/s00508-014-0538-0

Mikolašević I, Orlic L, Milić S, Lukenda V, Rački S, Štimac D, i sur.. Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease. Wiener klinische Wochenschrift [Internet]. 2014. [pristupljeno 15.11.2024.];126(15-16):474-479. doi: 10.1007/s00508-014-0538-0

I. Mikolašević, et al., "Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease", Wiener klinische Wochenschrift, vol. 126, br. 15-16, str. 474-479, 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:568204. [Citirano: 15.11.2024.]

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Naslov (engleski)Nonalcoholic fatty liver disease (NAFLD) proven by transient elastography in patients with coronary heart disease
AutorIvana Mikolašević
AutorLidija Orlic
AutorSandra Milić
AutorVesna Lukenda
AutorSanjin Rački
AutorDavor Štimac
AutorErvin Avdovic
AutorLuka Zaputović
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
The relationship between nonalcoholic fatty liver disease (NAFLD) and coronary heart disease (CHD) is poorly understood. In the present study, we aimed to assess the frequency of NAFLD in CHD patients by using a new diagnostic tool: transient elastography (TE; Fibroscan(A (R))-CAP). Clarification of the present study may help to provide a new noninvasive tool for the assessment of NAFLD in this specific population of patients and may be of clinical importance in planning preventive strategies in high-risk patients. A total of 75 patients with proven CHD were enrolled. Liver stiffness was used to assess liver fibrosis, and controlled attenuation parameter (CAP) was used to detect and quantify liver steatosis by using Fibroscan(A (R)) (Echosens, Paris, France). By CAP being implemented on TE, both liver steatosis and fibrosis can be evaluated simultaneously. Of the 75 patients, 45 (60 %) had CAP > 238 dBm(-1) and, by definition, NAFLD. Among the patients with NAFLD, 24 (53.3 %) had, in addition, liver stiffness > 7 kPa. Analyzing the influence of the degree of liver steatosis (expressed by CAP values) on the degree of CHD (defined by single or multiple vessels involved), we found that patients with multiple vessels involved had higher CAP values (p = 0.002). Furthermore, we noticed that significantly more patients with multiple vessels involved had liver stiffness > 7 kPa (p < 0.0001) indicating the more severe form of NAFLD in those patients. The main finding of our study is that TE provides the opportunity of noninvasive screening for NAFLD in CHD patients, as it is a quick, simple, reliable, and repeatable method and more cost-effective than liver biopsy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaWiener klinische Wochenschrift
Brojčani podacivol. 126, br. 15-16, str. 474-479
p-ISSN0043-5325
e-ISSN1613-7671
DOIhttps://doi.org/10.1007/s00508-014-0538-0
URN:NBNurn:nbn:hr:184:568204
Datum objave publikacije2014
URL dokumentahttp://link.springer.com/10.1007/s00508-014-0538-0
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-09-20 07:15:53