prikaz prve stranice dokumenta Murine cytomegalovirus regulation of NKG2D ligands
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Murine cytomegalovirus regulation of NKG2D ligands
Medical Microbiology and Immunology, 197 (2008), 2; 159-166. urn:nbn:hr:184:246576
Lenac, Tihana; Arapović, Jurica; Traven, Luka; Krmpotić, Astrid; Jonjić, Stipan

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Lenac, T., Arapović, J., Traven, L., Krmpotić, A. i Jonjić, S. (2008). Murine cytomegalovirus regulation of NKG2D ligands. Medical Microbiology and Immunology, 197. (2), 159-166. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:246576

Lenac, Tihana, et al. "Murine cytomegalovirus regulation of NKG2D ligands." Medical Microbiology and Immunology, vol. 197, br. 2, 2008, str. 159-166. https://urn.nsk.hr/urn:nbn:hr:184:246576

Lenac, Tihana, Jurica Arapović, Luka Traven, Astrid Krmpotić i Stipan Jonjić. "Murine cytomegalovirus regulation of NKG2D ligands." Medical Microbiology and Immunology 197, br. 2 (2008): 159-166. https://urn.nsk.hr/urn:nbn:hr:184:246576

Lenac, T., et al. (2008) 'Murine cytomegalovirus regulation of NKG2D ligands', Medical Microbiology and Immunology, 197(2), str. 159-166. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:246576 (Datum pristupa: 04.12.2024.)

Lenac T, Arapović J, Traven L, Krmpotić A, Jonjić S. Murine cytomegalovirus regulation of NKG2D ligands. Medical Microbiology and Immunology [Internet]. 2008. [pristupljeno 04.12.2024.];197(2):159-166. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:246576

T. Lenac, J. Arapović, L. Traven, A. Krmpotić i S. Jonjić, "Murine cytomegalovirus regulation of NKG2D ligands", Medical Microbiology and Immunology, vol. 197, br. 2, str. 159-166, 2008. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:246576. [Citirano: 04.12.2024.]

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Podaci o radu
Naslov (engleski)Murine cytomegalovirus regulation of NKG2D ligands
AutorTihana Lenac
AutorJurica Arapović
AutorLuka Traven
AutorAstrid Krmpotić
AutorStipan Jonjić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Human cytomegalovirus (HCMV) is a ubiquitous pathogen that causes morbidity risk in immunologically suppressed and immunodeficient patients including congenital infections. Approaches to curb the consequences of HCMV infections are restricted by a lack of complete understanding of viral pathogenesis. The infection of mice with murine cytomegalovirus (MCMV) as a model of HCMV infection has been particularly useful in elucidating the role of innate and adaptive immune response mechanisms. A large number of cytomegalovirus genes modulate the innate and the adaptive host immune response. The products of several MCMV genes are involved in subverting the natural killer (NK) cell response by down-modulating cellular ligands for the NKG2D receptor expressed on NK cells and CD8(+) T cells. Mutant viruses lacking these immunoevasion genes are attenuated with respect to virus growth in vivo. Given the importance of the NKG2D receptor in controlling both NK- and T cell-mediated immunity, it is of tremendous importance to understand the molecular mechanisms and consequences of viral regulation of the NKG2D ligands.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedical Microbiology and Immunology
Brojčani podacivol. 197, br. 2, str. 159-166
p-ISSN0300-8584
URN:NBNurn:nbn:hr:184:246576
Datum objave publikacije2008
ProjektŠifra: 062-0621261-1263
Naziv (hrvatski): Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru
Naziv (engleski): Molecular mechanisms of immune evasion by cytomegalovirus
Voditelj: Stipan Jonjić
Pravna nadležnost: Hrvatska
Financijer: MZOS
Linija financiranja: ZP
ProjektŠifra: 062-0621261-1268
Naziv (hrvatski): Uloga imunosubverzivnih citomegalovirusnih gena u latenciji
Naziv (engleski): The role of cytomegalovirus immunoevasion genes in latency
Voditelj: Astrid Krmpotić
Pravna nadležnost: Hrvatska
Financijer: MZOS
Linija financiranja: ZP
URL dokumentahttp://bib.irb.hr/379153
Vrsta resursaTekst
Prava pristupaOgraničen pristup
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Datum i vrijeme pohrane2022-03-24 14:03:11