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The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study
Diabetes Therapy, 8 (2017), 4; 929-940. https://doi.org/10.1007/s13300-017-0288-x
Klobučar Majanović, Sanja; Janež, Andrej; Lefterov, Ivaylo; Tasić, Sanja; Cikač, Tatjana

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Klobučar Majanović, S., Janež, A., Lefterov, I., Tasić, S. i Cikač, T. (2017). The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study. Diabetes Therapy, 8. (4), 929-940. doi: 10.1007/s13300-017-0288-x

Klobučar Majanović, Sanja, et al. "The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study." Diabetes Therapy, vol. 8, br. 4, 2017, str. 929-940. https://doi.org/10.1007/s13300-017-0288-x

Klobučar Majanović, Sanja, Andrej Janež, Ivaylo Lefterov, Sanja Tasić i Tatjana Cikač. "The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study." Diabetes Therapy 8, br. 4 (2017): 929-940. https://doi.org/10.1007/s13300-017-0288-x

Klobučar Majanović, S., et al. (2017) 'The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study', Diabetes Therapy, 8(4), str. 929-940. doi: 10.1007/s13300-017-0288-x

Klobučar Majanović S, Janež A, Lefterov I, Tasić S, Cikač T. The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study. Diabetes Therapy [Internet]. 2017. [pristupljeno 15.11.2024.];8(4):929-940. doi: 10.1007/s13300-017-0288-x

S. Klobučar Majanović, A. Janež, I. Lefterov, S. Tasić i T. Cikač, "The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study", Diabetes Therapy, vol. 8, br. 4, str. 929-940, 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:831778. [Citirano: 15.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:831778
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Naslov (engleski)The Real-Life Effectiveness and Care Patterns of Diabetes Management Study for Balkan Region (Slovenia, Croatia, Serbia, Bulgaria): A Multicenter, Observational, Cross-Sectional Study
AutorSanja Klobučar Majanović
AutorAndrej Janež
AutorIvaylo Lefterov
AutorSanja Tasić
AutorTatjana Cikač
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
INTRODUCTION: Recent large randomized controlled trials highlighted the clinical significance of hypoglycemic episodes in the treatment of diabetes. The present survey was conducted to provide information from real-life practice on the incidence of hypoglycemia in type 2 diabetic patients treated with sulfonylureas. METHODS: This multicenter, observational, cross-sectional study collected data on incidence of side effects of sulfonylurea-based therapy in type 2 diabetic patients in four countries of the Balkan region (Slovenia, Croatia, Serbia, Bulgaria) from October 2014 to June 2015. RESULTS: Of the 608 who participated in the study, 573 patients (mean age 67.2 years, mean body mass index 29.9 kg/m2) met the inclusion/exclusion criteria. More than 90% of the patients were treated with the newer generation sulfonylureas- gliclazide or glimepiride-either as monotherapy or as dual therapy in combination with metformin. In total, 210 patients (36.6%) reported hypoglycemic episode(s) in the last 6 months. Mild episodes were reported by 132 patients (62.8%), moderate by 66 (31.2%), severe by 8 patients (4.0%), and very severe by 4 patients (2%), respectively. Overall, 171 patients (28.2%) reported body weight increase during the previous year. The mean reported body weight gain in this group of patients was 4.2 kg (SD 2.7, median 3). Among them, 68.1% gained less than 5 kg, 25.0% gained 5-9 kg, and the rest gained more than 10 kg. CONCLUSION: Although newer generation sulfonylureas are generally considered safe in terms of hypoglycemia, our data indicates their use is associated with substantial risk of hypoglycemia and weight gain. Clinicians should be mindful of these findings when prescribing SUs and inform patients about the risk of hypoglycemia.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDiabetes Therapy
Brojčani podacivol. 8, br. 4, str. 929-940
p-ISSN1869-6953
DOIhttps://doi.org/10.1007/s13300-017-0288-x
URN:NBNurn:nbn:hr:184:831778
Datum objave publikacije2017
URL dokumentahttp://bib.irb.hr/929968
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2022-03-11 15:20:00