prikaz prve stranice dokumenta Immunological characteristics of schizophrenia
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Immunological characteristics of schizophrenia
Psychiatria Danubina. Supplement, 30 (2018), S4; S180-S187. urn:nbn:hr:184:903803
Rubeša, Gordana; Gudelj, Lea; Dolores, Makovac

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Rubeša, G., Gudelj, L. i Dolores, M. (2018). Immunological characteristics of schizophrenia. Psychiatria Danubina. Supplement, 30. (S4), S180-S187. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:903803

Rubeša, Gordana, et al. "Immunological characteristics of schizophrenia." Psychiatria Danubina. Supplement, vol. 30, br. S4, 2018, str. S180-S187. https://urn.nsk.hr/urn:nbn:hr:184:903803

Rubeša, Gordana, Lea Gudelj i Makovac Dolores. "Immunological characteristics of schizophrenia." Psychiatria Danubina. Supplement 30, br. S4 (2018): S180-S187. https://urn.nsk.hr/urn:nbn:hr:184:903803

Rubeša, G., Gudelj, L. i Dolores, M. (2018) 'Immunological characteristics of schizophrenia', Psychiatria Danubina. Supplement, 30(S4), str. S180-S187. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:903803 (Datum pristupa: 24.12.2024.)

Rubeša G, Gudelj L, Dolores M. Immunological characteristics of schizophrenia. Psychiatria Danubina. Supplement [Internet]. 2018. [pristupljeno 24.12.2024.];30(S4):S180-S187. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:903803

G. Rubeša, L. Gudelj i M. Dolores, "Immunological characteristics of schizophrenia", Psychiatria Danubina. Supplement, vol. 30, br. S4, str. S180-S187, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:903803. [Citirano: 24.12.2024.]

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Podaci o radu
Naslov (engleski)Immunological characteristics of schizophrenia
AutorGordana Rubeša
AutorLea Gudelj
AutorMakovac Dolores
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za psihijatriju i psihološku medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Psihijatrija
Sažetak (engleski)
There are many theories about the etiology of schizophrenia. This paper presents the assumptions and latest findings about many immunological characteristics of schizophrenia. According to the neuroimunological theory, this disorder is due to neuroimunological disbalance, increased microglial activity and increased levels of proinflammatory cytokines. Studies have found that intrauterine infections in pregnant women have an effect on the fetal brain development, and that infections with rubella, measles, herpes virus, and toxoplasma are associeted with schizophrenia onset in adult life. In the first episode of schizophrenia and during exacerbation in the serum of the patient, an increased level of proinflammatory cytokines was found. Increased levels of IL-6, TNF-α and IL-1β, and decreased levels of anti-inflammatory cytokines, Il-10. Interleukin 6 levels increase in the psychotic phase of the disease and normalize after the antipsychotic drug treatment. Increased level of IL-6 is associated with severe cognitive impairment and it is more common with patients who had been without adequate treatment for a long time and patients with therapeutic- resistant schizophrenia. Treatment of schizophrenia could be improved by the introduction of anti-inflammatory drug in the therapy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Rad s konferencije
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaPsychiatria Danubina. Supplement
Brojčani podacivol. 30, br. S4, str. S180-S187
p-ISSN1332-1366
URN:NBNurn:nbn:hr:184:903803
Datum objave publikacije2018
URL dokumentahttp://bib.irb.hr/953746
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-21 13:44:34