Alzheimer's disease is a neurodegenerative disease and the most common cause of dementia in adults. It was first described in 1906 by Dr. Alois Alzheimer, a German neuropathologist and psychiatrist. It is a chronic, progressive brain disease where symptoms develop slowly, unnoticed and with time hinders daily functioning. One of the first and basic features of the disease is memory impairment, especially in the area of learning and recalling new informations. In addition, patients experience difficulties with language, concentration, organization and planning, visuospacial skills and orientation. Because of this symptoms patients can jeopardize themselves and others (management of machines, cars, leaving stove on). The exact cause of disease is unknown, but it is believed that for most people, Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the brain over time. Two of the hallmarks of Alzheimer's disease is the accumulation of amyloid plaques between nerve cells in the brain and neurofibrillary tangles (insoluble twisted fibers found inside the brain's cells). Its accumulation causes damage and death of neurons, which leads to the clinical manifestation of dementia. Alzheimer's disease is not easily diagnosed, and the basic approach to diagnosis is to exclude other potential causes of dementia, testing patient's mental status with various psychological tests, as well as search for specific changes with brain-imaging technologies. Although the disease is described over a century ago, treatment of Alzheimer's disease is still nonexistent. There is no drug that could stop degenerative process or regain lost function - therapy is symptomatic. Focus is on effective activities that have a stimulating effect on the brain, and helps with memory imapirment and mood.