prikaz prve stranice dokumenta Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies
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Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies
United European Gastroenterology Journal, 6 (2018), 8; 1206-1214. https://doi.org/10.1177/2050640618781168
Poropat, Goran; Archibugi, Livia; Korpela, Taija; Cárdenas-Jaén, Karina; de-Madaria, Enrique; Carpuso, Gabriele

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Poropat, G., Archibugi, L., Korpela, T., Cárdenas Jaén, K., de Madaria, E. i Carpuso, G. (2018). Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies. United European Gastroenterology Journal, 6. (8), 1206-1214. doi: 10.1177/2050640618781168

Poropat, Goran, et al. "Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies." United European Gastroenterology Journal, vol. 6, br. 8, 2018, str. 1206-1214. https://doi.org/10.1177/2050640618781168

Poropat, Goran, Livia Archibugi, Taija Korpela, Karina Cárdenas Jaén, Enrique de Madaria i Gabriele Carpuso. "Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies." United European Gastroenterology Journal 6, br. 8 (2018): 1206-1214. https://doi.org/10.1177/2050640618781168

Poropat, G., et al. (2018) 'Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies', United European Gastroenterology Journal, 6(8), str. 1206-1214. doi: 10.1177/2050640618781168

Poropat G, Archibugi L, Korpela T, Cárdenas Jaén K, de Madaria E, Carpuso G. Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies. United European Gastroenterology Journal [Internet]. 2018. [pristupljeno 03.12.2024.];6(8):1206-1214. doi: 10.1177/2050640618781168

G. Poropat, L. Archibugi, T. Korpela, K. Cárdenas Jaén, E. de Madaria i G. Carpuso, "Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies", United European Gastroenterology Journal, vol. 6, br. 8, str. 1206-1214, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:293058. [Citirano: 03.12.2024.]

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Podaci o radu
Naslov (engleski)Statin use is not associated with an increased risk of acute pancreatitis-A meta-analysis of observational studies
AutorGoran Poropat
AutorLivia Archibugi
AutorTaija Korpela
AutorKarina Cárdenas-Jaén
AutorEnrique de-Madaria
AutorGabriele Carpuso
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
BACKGROUND: Statins are perceived as potential etiological factors for acute pancreatitis (AP), but recent evidence suggests the opposite. Our aim was to evaluate the association between statin use and risk of AP in observational studies. METHODS: Medline, Scopus, and Web of Science were searched for cohort (C) and case-control (CC) studies evaluating statins as intervention and AP as outcome. Pooled adjusted odds ratios (ORs) with corresponding 95% confidence intervals (CIs) were calculated. RESULTS: Thirteen studies (seven CC, six C) with 34,899 AP patients and 5,377,894 controls were included. Prevalence of statin use was 9.8% among AP patients and 25% among controls. Pooled adjusted OR was 1.00 (95% CI = 0.63 to 1.59) with considerable heterogeneity (I 2 = 98%). CC studies were associated with increased AP risk (OR = 1.33; 95% CI = 1.20 to 1.47), unlike C studies (OR = 0.69; 95% CI = 0.37 to 1.31). No association with increased risk was found for studies from Western countries (OR = 0.90; 95% CI = 0.52 to 1.56), unlike for studies conducted in Asia (OR = 1.39; 95% CI = 1.10 to 1.75). CONCLUSION: Statin use is not associated with increased risk of AP. Increased risk was limited to CC studies, which are more prone to bias, while C studies showed no global effect. Further research is needed to clarify whether statin type, dosage, treatment duration or AP etiology might account for this difference
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaUnited European Gastroenterology Journal
Brojčani podacivol. 6, br. 8, str. 1206-1214
p-ISSN2050-6406
e-ISSN2050-6414
DOIhttps://doi.org/10.1177/2050640618781168
URN:NBNurn:nbn:hr:184:293058
Datum objave publikacije2018
URL dokumentahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169058/pdf/10.1177_2050640618781168.pdf
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2018-10-10 21:09:56