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Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease
Acta Dermato-Venereologica Supplementum, 211 (2000); 14-16. https://doi.org/10.1080/00015550050500059
Prpić, Larisa; Štrbo, Nataša; Sotošek, Vlatka; Gruber, Franjo; Podack, Eckhard R.; Rukavina, Daniel

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Prpić, L., Štrbo, N., Sotošek, V., Gruber, F., Podack, E. R. i Rukavina, D. (2000). Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease. Acta Dermato-Venereologica Supplementum, 211., 14-16. doi: 10.1080/00015550050500059

Prpić, Larisa, et al. "Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease." Acta Dermato-Venereologica Supplementum, vol. 211, 2000, str. 14-16. https://doi.org/10.1080/00015550050500059

Prpić, Larisa, Nataša Štrbo, Vlatka Sotošek, Franjo Gruber, Eckhard R. Podack i Daniel Rukavina. "Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease." Acta Dermato-Venereologica Supplementum 211 (2000): 14-16. https://doi.org/10.1080/00015550050500059

Prpić, L., et al. (2000) 'Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease', Acta Dermato-Venereologica Supplementum, 211, str. 14-16. doi: 10.1080/00015550050500059

Prpić L, Štrbo N, Sotošek V, Gruber F, Podack ER, Rukavina D. Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease. Acta Dermato-Venereologica Supplementum [Internet]. 2000. [pristupljeno 12.11.2024.];211:14-16. doi: 10.1080/00015550050500059

L. Prpić, N. Štrbo, V. Sotošek, F. Gruber, E. R. Podack i D. Rukavina, "Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease", Acta Dermato-Venereologica Supplementum, vol. 211, str. 14-16, 2000. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:001688. [Citirano: 12.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:001688
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Podaci o radu
Naslov (engleski)Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease
AutorLarisa Prpić
AutorNataša Štrbo
AutorVlatka Sotošek
AutorFranjo Gruber
AutorEckhard R. Podack
AutorDaniel Rukavina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za dermatovenerologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Dermatovenerologija
Sažetak (engleski)
There are very few data concerning the role played by cellmediated cytotoxicity, particularly at the molecular level, in the course of psoriasis. Both cytotoxic T lymphocytes (CTL) and natural killer cells contain in their granules the cytolytic protein perforin, a mediator in cell-mediated cytotoxicity reactions. The aim of this study was to analyze perforin expression in various sets and subsets of perforin-positive peripheral blood lymphocytes in 17 patients with chronic psoriasis vulgaris in the exacerbation phase. The results were compared with those of an age- and sex-matched healthy control group (n= 21). Perforin (intracellular antigen) and cell surface antigens were detected using the simultaneous double-staining method. We found a signi®cant increase in perforin (P) expression in the patient group for CTL (CD3+ P+ cells), which are located mostly in the CD8+ population of T lymphocytes (CD8+ P+ ).
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaActa Dermato-Venereologica Supplementum
Brojčani podacivol. 211, str. 14-16
p-ISSN0365-8341
DOIhttps://doi.org/10.1080/00015550050500059
URN:NBNurn:nbn:hr:184:001688
Datum objave publikacije2000
URL dokumentahttps://www.medicaljournals.se/acta/content/abstract/10.1080/00015550050500059
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2018-06-28 08:51:23