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The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature
Case Reports in Oncology, 18 (2024), 1; 7-14. https://doi.org/10.1159/000541419
Bukovica Petrc, Anamarija; Salopek, Tihana; Skočilić, Iva; Zahirovic, Dag; Orlić, Lidija; Bubić, Ivan; Matana-Kaštelan, Zrinka; Francetić, Sara; Lisica, Karla; Mikolašević, Ivana

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Bukovica Petrc, A., Salopek, T., Skočilić, I., Zahirovic, D., Orlić, L., Bubić, I. ... Mikolašević, I. (2024). The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature. Case Reports in Oncology, 18. (1), 7-14. doi: 10.1159/000541419

Bukovica Petrc, Anamarija, et al. "The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature." Case Reports in Oncology, vol. 18, br. 1, 2024, str. 7-14. https://doi.org/10.1159/000541419

Bukovica Petrc, Anamarija, Tihana Salopek, Iva Skočilić, Dag Zahirovic, Lidija Orlić, Ivan Bubić, Zrinka Matana Kaštelan, Sara Francetić, Karla Lisica i Ivana Mikolašević. "The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature." Case Reports in Oncology 18, br. 1 (2024): 7-14. https://doi.org/10.1159/000541419

Bukovica Petrc, A., et al. (2024) 'The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature', Case Reports in Oncology, 18(1), str. 7-14. doi: 10.1159/000541419

Bukovica Petrc A, Salopek T, Skočilić I, Zahirovic D, Orlić L, Bubić I, i sur.. The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature. Case Reports in Oncology [Internet]. 19.12.2024. [pristupljeno 05.03.2025.];18(1):7-14. doi: 10.1159/000541419

A. Bukovica Petrc, et al., "The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature", Case Reports in Oncology, vol. 18, br. 1, str. 7-14, Prosinac 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:205295. [Citirano: 05.03.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:205295
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Naslov (engleski)The Use of Liver Support System Devices in Acute Liver Failure as a Consequence of Metastatic Melanoma in the Liver: A Case Report and Review of the Literature
AutorAnamarija Bukovica Petrc
AutorTihana Salopek
AutorIva Skočilić
AutorDag Zahirovic
AutorLidija Orlić
AutorIvan Bubić
AutorZrinka Matana-Kaštelan
AutorSara Francetić
AutorKarla Lisica
AutorIvana Mikolašević
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Onkologija
Sažetak (engleski)
Introduction: Melanoma often metastasizes to the liver, leading to significant morbidity and mortality. Liver injury can also occur due to hepatitis caused by immunotherapy used in the treatment of melanoma. Case Presentation: This case report presents a 38-year-old male diagnosed with advanced melanoma who experienced acute liver failure (ALF) initially thought to be a side effect of immunotherapy. Despite following aggressive supportive care as per the latest guidelines, the patient’s condition deteriorated rapidly. It was discovered that the patient had liver metastases. As the tumor had a positive BRAF mutation, we opted for invasive treatment with therapeutic plasma exchange to restore liver function and create the conditions for initiating treatment with BRAF/MEK inhibitors. After the use of a liver support device, the liver function was resolved, and a BRAF/MEK inhibitor was introduced. After 2 months of targeted therapy, a favorable effect and good melanoma control are observed. Conclusion: The report underscores the complexity of managing melanoma with liver metastasis and the urgent need for advancements in treatment modalities ALF in oncology patients. We suggest that invasive treatment methods, such as liver support system devices, should be considered in well-selected oncology patients, even in advanced stages of disease.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCase Reports in Oncology
Brojčani podacivol. 18, br. 1, str. 7-14
e-ISSN1662-6575
DOIhttps://doi.org/10.1159/000541419
URN:NBNurn:nbn:hr:184:205295
Datum objave publikacije2024-12-19
URL dokumentahttps://karger.com/doi/10.1159/000541419
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2025-03-05 12:51:14