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Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies
Epigenomes, 8 (2024), 3; 34. https://doi.org/10.3390/epigenomes8030034
Saftić Martinović, Lara; Mladenić, Tea; Lovrić, Dora; Ostojić, Saša; Dević Pavlić, Sanja

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Saftić Martinović, L., Mladenić, T., Lovrić, D., Ostojić, S. i Dević Pavlić, S. (2024). Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies. Epigenomes, 8. (3). doi: 10.3390/epigenomes8030034

Saftić Martinović, Lara, et al. "Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies." Epigenomes, vol. 8, br. 3, 2024. https://doi.org/10.3390/epigenomes8030034

Saftić Martinović, Lara, Tea Mladenić, Dora Lovrić, Saša Ostojić i Sanja Dević Pavlić. "Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies." Epigenomes 8, br. 3 (2024). https://doi.org/10.3390/epigenomes8030034

Saftić Martinović, L., et al. (2024) 'Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies', Epigenomes, 8(3). doi: 10.3390/epigenomes8030034

Saftić Martinović L, Mladenić T, Lovrić D, Ostojić S, Dević Pavlić S. Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies. Epigenomes [Internet]. 05.09.2024. [pristupljeno 04.12.2024.];8(3). doi: 10.3390/epigenomes8030034

L. Saftić Martinović, T. Mladenić, D. Lovrić, S. Ostojić i S. Dević Pavlić, "Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies", Epigenomes, vol. 8, br. 3, Rujan 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:835586. [Citirano: 04.12.2024.]

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Naslov (engleski)Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies
AutorLara Saftić Martinović
AutorTea Mladenić
AutorDora Lovrić
AutorSaša Ostojić
AutorSanja Dević Pavlić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Genetika, genomika i proteomika čovjeka
Sažetak (engleski)
Infertility is a complex condition caused by a combination of genetic, environmental, and lifestyle factors. Recent advances in epigenetics have highlighted the importance of epigenetic changes in fertility regulation. This review aims to provide a comprehensive overview of the epigenetic mechanisms involved in infertility, with a focus on DNA methylation, histone modification, and non-coding RNAs. We investigate the specific epigenetic events that occur during gametogenesis, with a focus on spermatogenesis and oogenesis as distinct processes. Furthermore, we investigate how environmental factors such as diet, stress, and toxin exposure can influence these epigenetic changes, potentially leading to infertility. The second part of the review explores epigenetic changes as therapeutic targets for infertility. Emerging therapies that modulate epigenetic marks present promising opportunities for fertility restoration, particularly in spermatogenesis. By summarizing current research findings, this review emphasizes the importance of understanding epigenetic contributions to infertility. Our discussion aims to lay the groundwork for future research directions and clinical applications in reproductive health.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaEpigenomes
Brojčani podacivol. 8, br. 3, 34
e-ISSN2075-4655
DOIhttps://doi.org/10.3390/epigenomes8030034
URN:NBNurn:nbn:hr:184:835586
Datum objave publikacije2024-09-05
URL dokumentahttps://www.mdpi.com/2075-4655/8/3/34
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-09-13 10:51:22