prikaz prve stranice dokumenta Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare
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Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare
Processes, 12 (2024), 1; 111. https://doi.org/10.3390/pr12010111
Peruč, Dolores; Štifter-Vretenar, Sanja; Planinić, Ana; Gobin, Ivana

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Peruč, D., Štifter Vretenar, S., Planinić, A. i Gobin, I. (2024). Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare. Processes, 12. (1). doi: 10.3390/pr12010111

Peruč, Dolores, et al. "Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare." Processes, vol. 12, br. 1, 2024. https://doi.org/10.3390/pr12010111

Peruč, Dolores, Sanja Štifter Vretenar, Ana Planinić i Ivana Gobin. "Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare." Processes 12, br. 1 (2024). https://doi.org/10.3390/pr12010111

Peruč, D., et al. (2024) 'Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare', Processes, 12(1). doi: 10.3390/pr12010111

Peruč D, Štifter Vretenar S, Planinić A, Gobin I. Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare. Processes [Internet]. 02.01.2024. [pristupljeno 20.12.2024.];12(1). doi: 10.3390/pr12010111

D. Peruč, S. Štifter Vretenar, A. Planinić i I. Gobin, "Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare", Processes, vol. 12, br. 1, Siječanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:815932. [Citirano: 20.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:815932
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Podaci o radu
Naslov (engleski)Combined Application of Juniperus communis Essential Oil and Amikacin, Clarithromycin and Rifampicin against Mycobacterium avium and Mycobacterium intracellulare
AutorDolores Peruč
AutorSanja Štifter-Vretenar
AutorAna Planinić
AutorIvana Gobin
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za mikrobiologiju i parazitologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
The group of nontuberculous mycobacteria (NTM) includes about 200 mycobacteria that are widespread in the natural environment as free-living saprophytic bacteria, commensals or symbionts. NTM, also referred to as atypical mycobacteria, are mostly apathogenic; nowadays, they are increasingly important environmental opportunistic pathogens. This study continues the work of previous studies which investigated the individual and synergistic effect of different essential oils (EOs) on NTM. The aim was to investigate the effect of the interaction of the common juniper (Juniperus communis) EO and the antimicrobials, amikacin, clarithromycin and rifampicin, against Mycobacterium avium and M. intracellulare using the checkerboard synergy method in an enriched Middlebrook 7H9 broth. Morphological changes of treated NTM cells were observed with a transmission electron microscope. The most synergistic combinations were found at subinhibitory concentrations of the common juniper EO and rifampicin against both tested NTM and this EO and clarithromycin against M. avium. A slightly smaller number of synergistic effects on both NTM were found using a combination of this EO and amikacin. Combinations of clarithromycin and the common juniper EO showed no synergism against M. intracellulare. The exposure of both NTM to synergistic combinations of this EO and antimicrobials caused significant morphological changes in mycobacterial cells. Synergism with the combined use of EOs and antimicrobials allows the use of low effective concentrations via the sustained antimicrobial effect of the tested substances, but with potentially reduced toxicity.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaProcesses
Brojčani podacivol. 12, br. 1, 111
e-ISSN2227-9717
DOIhttps://doi.org/10.3390/pr12010111
URN:NBNurn:nbn:hr:184:815932
Datum objave publikacije2024-01-02
ProjektŠifra: uniri-biomed-18-171
Naziv (hrvatski): Oportunistički patogeni vodoopskrbnog sustava: novi izazov u obradi voda
Naziv (engleski): Opportunistic Premise Plumbing Pathogens: New Challenge for Water Treatment
Voditelj: Ivana Gobin
Pravna nadležnost: Hrvatska
Financijer: NadSve
Linija financiranja: Nema
URL dokumentahttps://www.mdpi.com/2227-9717/12/1/111
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-01-03 12:47:20