prikaz prve stranice dokumenta Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis
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Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis
Osteoarthritis and Cartilage, 21 (2013), 11; 1724-1730. https://doi.org/10.1016/j.joca.2013.06.030
Bobinac, Dragica; Marinović, Marin; Bazdulj, E.; Cvijanović, Olga; Ćelic, T.anja; Marić, Ivana; Španjol, Josip; Cicvarić, Tedi

Citirajte ovaj rad

Bobinac, D., Marinović, M., Bazdulj, E., Cvijanović, O., Ćelic, T., Marić, I. ... Cicvarić, T. (2013). Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis. Osteoarthritis and Cartilage, 21. (11), 1724-1730. doi: 10.1016/j.joca.2013.06.030

Bobinac, Dragica, et al. "Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis." Osteoarthritis and Cartilage, vol. 21, br. 11, 2013, str. 1724-1730. https://doi.org/10.1016/j.joca.2013.06.030

Bobinac, Dragica, Marin Marinović, E. Bazdulj, Olga Cvijanović, T.anja Ćelic, Ivana Marić, Josip Španjol i Tedi Cicvarić. "Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis." Osteoarthritis and Cartilage 21, br. 11 (2013): 1724-1730. https://doi.org/10.1016/j.joca.2013.06.030

Bobinac, D., et al. (2013) 'Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis', Osteoarthritis and Cartilage, 21(11), str. 1724-1730. doi: 10.1016/j.joca.2013.06.030

Bobinac D, Marinović M, Bazdulj E, Cvijanović O, Ćelic T, Marić I, i sur.. Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis. Osteoarthritis and Cartilage [Internet]. 11.2013. [pristupljeno 23.12.2024.];21(11):1724-1730. doi: 10.1016/j.joca.2013.06.030

D. Bobinac, et al., "Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis", Osteoarthritis and Cartilage, vol. 21, br. 11, str. 1724-1730, Studeni 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:528728. [Citirano: 23.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:528728
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Podaci o radu
Naslov (engleski)Microstructural alterations of femoral head articular cartilage and subchondral bone in osteoarthritis and osteoporosis
AutorDragica Bobinac
AutorMarin Marinović
AutorE. Bazdulj
AutorOlga Cvijanović
AutorT.anja Ćelic
AutorIvana Marić
AutorJosip Španjol
AutorTedi Cicvarić
Autorova ustanova(Klinički bolnički centar Rijeka)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anatomiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za kirurgiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Anatomija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Objective: Explore whether osteoporosis (OP) in humans influences the morphological status of the articular cartilage and the subchondral bone. Explore the relationship between the macroscopic aspect of the articular surface and the rate of microscopic changes of both the cartilage and the subchondral bone in OP and osteoarthritis (OA). Methods: Femoral heads after total hip replacement were obtained from patients with OP or hip OA (OP, n=56; OA, n=12). Cartilage degeneration was assessed using the Mankin grading system whereas subchondral bone was evaluated using histomorphometry and Micro-computed Tomography (μCT) scanning system. Thickness of the cartilage layers and subchondral cortical bone (SCB) was measured. Results: Samples with higher total Mankin score have significantly reduced cartilage thickness. Mankin score differed between all OP specimens. In OP samples with lower Mankin scores the thickness of SCBshows a trend of an increase caused by increased levels of bone remodeling. In OP samples with higher Mankin scores we observed thinning of SCB. Structural indices of subchondral trabecular bone (STB) were significantly lower in OP than in OA samples. Conclusion: Thinning of SCB, found in OP samples with higher Mankin scores could be related with the progression of the cartilage degeneration indicating an early-stage OA. Increased levels of bone remodeling and evidently changed morphology of subchondral bone found in OP samples with lower Mankin score indicated that bony bed level must have a role in the progression of the cartilage degeneration.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaOsteoarthritis and Cartilage
Brojčani podacivol. 21, br. 11, str. 1724-1730
p-ISSN1063-4584
DOIhttps://doi.org/10.1016/j.joca.2013.06.030
URN:NBNurn:nbn:hr:184:528728
Datum objave publikacije2013-11
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S1063458413008662
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-11-11 07:54:47