prikaz prve stranice dokumenta Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients
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Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients
International urology and nephrology, 48 (2016), 7; 1145-1154. https://doi.org/10.1007/s11255-016-1275-2
Kocijančić, Marija; Čubranić, Zlatko; Vujičić, Božidar; Rački, Sanjin; Dvornik, Štefica; Zaputović, Luka

Citirajte ovaj rad

Kocijančić, M., Čubranić, Z., Vujičić, B., Rački, S., Dvornik, Š. i Zaputović, L. (2016). Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients. International urology and nephrology, 48. (7), 1145-1154. doi: 10.1007/s11255-016-1275-2

Kocijančić, Marija, et al. "Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients." International urology and nephrology, vol. 48, br. 7, 2016, str. 1145-1154. https://doi.org/10.1007/s11255-016-1275-2

Kocijančić, Marija, Zlatko Čubranić, Božidar Vujičić, Sanjin Rački, Štefica Dvornik i Luka Zaputović. "Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients." International urology and nephrology 48, br. 7 (2016): 1145-1154. https://doi.org/10.1007/s11255-016-1275-2

Kocijančić, M., et al. (2016) 'Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients', International urology and nephrology, 48(7), str. 1145-1154. doi: 10.1007/s11255-016-1275-2

Kocijančić M, Čubranić Z, Vujičić B, Rački S, Dvornik Š, Zaputović L. Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients. International urology and nephrology [Internet]. 2016. [pristupljeno 07.12.2024.];48(7):1145-1154. doi: 10.1007/s11255-016-1275-2

M. Kocijančić, Z. Čubranić, B. Vujičić, S. Rački, Š. Dvornik i L. Zaputović, "Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients", International urology and nephrology, vol. 48, br. 7, str. 1145-1154, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:623550. [Citirano: 07.12.2024.]

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Naslov (engleski)Soluble intracellular adhesion molecule-1 and omentin-1 as potential biomarkers of subclinical atherosclerosis in hemodialysis patients
AutorMarija Kocijančić
AutorZlatko Čubranić
AutorBožidar Vujičić
AutorSanjin Rački
AutorŠtefica Dvornik
AutorLuka Zaputović
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za kliničko-laboratorijsku dijagnostiku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za urologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Purpose. Atherosclerotic cardiovascular complications represent significant cause of mortality in hemodialysis (HD) patients. The aims of this study were to: (a) investigate association of sICAM-1, sVCAM-1, omentin-1 and other non-traditional risk factors with subclinical atherosclerosis ; (b) examine the diagnostic value of these specific markers in the early detection of subclinical atherosclerosis ; and (c) examine their role as predictors of mortality in group of patients with subclinical atherosclerosis on regular HD. Materials and methods. Starting from November 2011, a cohort of 210 HD patients participated in this 3-year follow-up study. The subjects were divided into three groups according to the presence of atherosclerosis. Atherosclerotic disease was assessed by measuring carotid intima-media thickness (IMT). Samplings were withdrawn at baseline and thereafter every 12 months until the end of follow-up. Results. IMT showed weak correlation with sICAM-1 (r = 0.39, P = 0.001), sVCAM-1 (r = 0.27, P = 0.015) and omentin-1 (r = −0.25, P = 0.020), and also omentin-1 showed good correlation with parameters of systolic and diastolic function (r = 0.52, P = 0.001 and r = 0.51, P = 0.001). Multivariate analysis showed that sICAM-1 and sVCAM-1 concentrations were a strong independent correlate of IMT (P = 0.031 and P = 0.010, respectively). The Cox proportional analysis showed that sICAM-1 and omentin-1 concentrations were strong predictors of cardiovascular death (HR 1.85, CI 1.18–2.32, P = 0.021 and HR 4.14, CI 1.38–12.1, P = 0.004, respectively) and that serial measurements of these markers predict IMT progression (HR 1.98, 95% CI 1.21–2.38, P < 0.002 and HR 2.91, 95% CI 1.57–4.72, P < 0.001, respectively). Conclusions. Our study demonstrated that sICAM-1 and omentin-1 levels are strong predictors of cardiovascular death in HD patients with subclinical atherosclerosis.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational urology and nephrology
Brojčani podacivol. 48, br. 7, str. 1145-1154
p-ISSN0301-1623
DOIhttps://doi.org/10.1007/s11255-016-1275-2
URN:NBNurn:nbn:hr:184:623550
Datum objave publikacije2016
URL dokumentahttp://bib.irb.hr/855918
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-03-09 12:45:54