prikaz prve stranice dokumenta Melanoma can control development of metastasis – Fact or myth?
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Melanoma can control development of metastasis – Fact or myth?
Medical Hypotheses, 89 (2016); 65-67. https://doi.org/10.1016/j.mehy.2016.02.009
Čabrijan, Leo; Batinac, Tanja; Lipozenčić, Jasna

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Čabrijan, L., Batinac, T. i Lipozenčić, J. (2016). Melanoma can control development of metastasis – Fact or myth?. Medical Hypotheses, 89., 65-67. doi: 10.1016/j.mehy.2016.02.009

Čabrijan, Leo, et al. "Melanoma can control development of metastasis – Fact or myth?." Medical Hypotheses, vol. 89, 2016, str. 65-67. https://doi.org/10.1016/j.mehy.2016.02.009

Čabrijan, Leo, Tanja Batinac i Jasna Lipozenčić. "Melanoma can control development of metastasis – Fact or myth?." Medical Hypotheses 89 (2016): 65-67. https://doi.org/10.1016/j.mehy.2016.02.009

Čabrijan, L., Batinac, T. i Lipozenčić, J. (2016) 'Melanoma can control development of metastasis – Fact or myth?', Medical Hypotheses, 89, str. 65-67. doi: 10.1016/j.mehy.2016.02.009

Čabrijan L, Batinac T, Lipozenčić J. Melanoma can control development of metastasis – Fact or myth?. Medical Hypotheses [Internet]. 04.2016. [pristupljeno 04.11.2024.];89:65-67. doi: 10.1016/j.mehy.2016.02.009

L. Čabrijan, T. Batinac i J. Lipozenčić, "Melanoma can control development of metastasis – Fact or myth?", Medical Hypotheses, vol. 89, str. 65-67, Travanj 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:707956. [Citirano: 04.11.2024.]

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Podaci o radu
Naslov (engleski)Melanoma can control development of metastasis – Fact or myth?
AutorLeo Čabrijan
AutorTanja Batinac
AutorJasna Lipozenčić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za dermatovenerologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Dermatovenerologija
Sažetak (engleski)
Abstract The malignant melanoma spreading process cannot explain occurrence of metastases several years following local surgical therapy of primary malignancy. But, this complex process of delayed metastases is still challenging and not completely understood. We hypotheses that melanoma metastases occur early in disease, probably at the same time with the occurrence of the primary melanoma. We suggest that dissemination of metastatic "seed cells" occur at an early stage of the disease together with the development of primary melanoma and cannot be detected by standard diagnostic methods. These cells are masked between healthy cells and have the potential to proceed in true metastasis following the activation triggered by signal from primary tumor or other source. Other possibility includes the existence of two different genes, one responsible for development of primary melanoma, and the other with a roll in development of metastases. We believe that future investigation should be directed toward better understanding of mechanisms involved in metastases development keeping in mind that melanoma behavior is irrational and defies logical thinking.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedical Hypotheses
Brojčani podacivol. 89, str. 65-67
p-ISSN0306-9877
DOIhttps://doi.org/10.1016/j.mehy.2016.02.009
URN:NBNurn:nbn:hr:184:707956
Datum objave publikacije2016-04
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S0306987716000517
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-18 14:07:54