prikaz prve stranice dokumenta Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia
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Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia
Collegium antropologicum, 36 supplement 2 (2012), 2; 87-91. urn:nbn:hr:184:713367
Braut, Tamara; Kujundžić, Milodar; Vukelić, Jelena; Manestar, Dubravko; Krstulja, Mira; Starčević, Radan; Grahovac, Blaženka

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Braut, T., Kujundžić, M., Vukelić, J., Manestar, D., Krstulja, M., Starčević, R. i Grahovac, B. (2012). Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia. Collegium antropologicum, 36 supplement 2. (2), 87-91. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:713367

Braut, Tamara, et al. "Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia." Collegium antropologicum, vol. 36 supplement 2, br. 2, 2012, str. 87-91. https://urn.nsk.hr/urn:nbn:hr:184:713367

Braut, Tamara, Milodar Kujundžić, Jelena Vukelić, Dubravko Manestar, Mira Krstulja, Radan Starčević i Blaženka Grahovac. "Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia." Collegium antropologicum 36 supplement 2, br. 2 (2012): 87-91. https://urn.nsk.hr/urn:nbn:hr:184:713367

Braut, T., et al. (2012) 'Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia', Collegium antropologicum, 36 supplement 2(2), str. 87-91. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:713367 (Datum pristupa: 09.12.2024.)

Braut T, Kujundžić M, Vukelić J, Manestar D, Krstulja M, Starčević R, i sur.. Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia. Collegium antropologicum [Internet]. 2012. [pristupljeno 09.12.2024.];36 supplement 2(2):87-91. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:713367

T. Braut, et al., "Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia", Collegium antropologicum, vol. 36 supplement 2, br. 2, str. 87-91, 2012. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:713367. [Citirano: 09.12.2024.]

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Naslov (engleski)Gene Amplification of Epidermal Growth Factor Receptor in Atypical Glottic Hyperplasia
AutorTamara Braut
AutorMilodar Kujundžić
AutorJelena Vukelić
AutorDubravko Manestar
AutorMira Krstulja
AutorRadan Starčević
AutorBlaženka Grahovac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za otorinolaringologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Otorinolaringologija
Sažetak (engleski)
The study searched for epidermal growth factor receptor (EGFR) gene amplification in hyperplastic glottis lesions. After classical pathohistological findings of hematoxylin-eosin (HE) slides and quantitative immunohistochemical (IHC) analysis, fluorescent in situ hybridization (FISH) was used on tissue microarrays of laryngeal hyperplastic tissue ranging from normal mucosa to abnormal and atypical hyperplastic lesions. FISH analysis of two atypical hyperplastic lesions discovered the amplification of EGFR gene while it was not found in simple and abnormal hyperplastic lesions. The results may indicate that EGFR gene amplifications could possibly correlate with the histopathologic picture. Tissue samples burdened with specific oncogen signatures like EGFR gene amplification could be detected in precancerous lesion. This might improve follow-up and treatment protocols of glottic lesions which are an everyday problem for ENT practitioners. Further research is mandatory to confirm our findings.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCollegium antropologicum
Brojčani podacivol. 36 supplement 2, br. 2, str. 87-91
p-ISSN0350-6134
e-ISSN1848-9486
URN:NBNurn:nbn:hr:184:713367
Datum objave publikacije2012
URL dokumentahttps://hrcak.srce.hr/96462
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 3.0 (CC BY 3.0)
Datum i vrijeme pohrane2022-02-02 08:42:41