prikaz prve stranice dokumenta Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase
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Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase
Acta medica Okayama, 59 (2005), 4; 153-159. urn:nbn:hr:184:671192
Bralić, Marina; Muhvić Urek, Miranda; Stemberga, Valter; Golemac, Mijo; Jurković, Slaven; Borčić, Josipa; Braut, Alen; Tomac, Jelena

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Bralić, M., Muhvić Urek, M., Stemberga, V., Golemac, M., Jurković, S., Borčić, J. ... Tomac, J. (2005). Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase. Acta medica Okayama, 59. (4), 153-159. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:671192

Bralić, Marina, et al. "Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase." Acta medica Okayama, vol. 59, br. 4, 2005, str. 153-159. https://urn.nsk.hr/urn:nbn:hr:184:671192

Bralić, Marina, Miranda Muhvić Urek, Valter Stemberga, Mijo Golemac, Slaven Jurković, Josipa Borčić, Alen Braut i Jelena Tomac. "Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase." Acta medica Okayama 59, br. 4 (2005): 153-159. https://urn.nsk.hr/urn:nbn:hr:184:671192

Bralić, M., et al. (2005) 'Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase', Acta medica Okayama, 59(4), str. 153-159. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:671192 (Datum pristupa: 11.11.2024.)

Bralić M, Muhvić Urek M, Stemberga V, Golemac M, Jurković S, Borčić J, i sur.. Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase. Acta medica Okayama [Internet]. 2005. [pristupljeno 11.11.2024.];59(4):153-159. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:671192

M. Bralić, et al., "Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase", Acta medica Okayama, vol. 59, br. 4, str. 153-159, 2005. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:671192. [Citirano: 11.11.2024.]

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Podaci o radu
Naslov (engleski)Cell Death and Cell Proliferation in Mouse Submandibular Gland during Early Post-irradiation Phase
AutorMarina Bralić
AutorMiranda Muhvić Urek
AutorValter Stemberga
AutorMijo Golemac
MBZ: 247605
AutorSlaven Jurković
AutorJosipa Borčić
AutorAlen Braut
AutorJelena Tomac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za onkologiju i radioterapiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za stomatološku protetiku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za sudsku medicinu i kriminalistiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
The effects of irradiation on different cell compartments in submandibular gland were analyzed in adult C57BL/6 mice exposed to X-ray irradiation and followed up for 10 days. Apoptosis was quantified using terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-digoxigenin nick end labeling method (TUNEL). Cell proliferation was detected using immunohistochemistry for proliferating cell nuclear antigen (PCNA). Radiation induced apoptosis occurred rapidly, with maximum observed 3 days post-irradiation. The percentage of apoptotic cells increased with the irradiation dose. One-day post-irradiation cell proliferation was significantly reduced in comparison to sham-irradiated controls. After post-irradiation arrest of the cell cycle, proliferation increased in all gland compartments reaching the maximum at day 6 post-irradiation. Proliferation response was equivalent with dose of irradiation. We suggest that reason for gland dysfunction could be co existing of high apoptotic and proliferative activity that is going on in irradiated gland.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaActa medica Okayama
Brojčani podacivol. 59, br. 4, str. 153-159
p-ISSN0386-300X
URN:NBNurn:nbn:hr:184:671192
Datum objave publikacije2005
URL dokumentahttp://bib.irb.hr/210523
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2020-04-19 19:17:37