prikaz prve stranice dokumenta Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands
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Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands
Journal of Virology, 87 (2013), 6; 3592-3596. https://doi.org/10.1128/JVI.02657-12
Handke, W.; Luig, C.; Popović, Branka; Krmpotić, Astrid; Jonjić, Stipan; Brune, Wolfram

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Handke, W., Luig, C., Popović, B., Krmpotić, A., Jonjić, S. i Brune, W. (2013). Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands. Journal of Virology, 87. (6), 3592-3596. doi: 10.1128/JVI.02657-12

Handke, W., et al. "Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands." Journal of Virology, vol. 87, br. 6, 2013, str. 3592-3596. https://doi.org/10.1128/JVI.02657-12

Handke, W., C. Luig, Branka Popović, Astrid Krmpotić, Stipan Jonjić i Wolfram Brune. "Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands." Journal of Virology 87, br. 6 (2013): 3592-3596. https://doi.org/10.1128/JVI.02657-12

Handke, W., et al. (2013) 'Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands', Journal of Virology, 87(6), str. 3592-3596. doi: 10.1128/JVI.02657-12

Handke W, Luig C, Popović B, Krmpotić A, Jonjić S, Brune W. Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands. Journal of Virology [Internet]. 09.01.2013. [pristupljeno 06.11.2024.];87(6):3592-3596. doi: 10.1128/JVI.02657-12

W. Handke, C. Luig, B. Popović, A. Krmpotić, S. Jonjić i W. Brune, "Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands", Journal of Virology, vol. 87, br. 6, str. 3592-3596, Siječanj 2013. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:801946. [Citirano: 06.11.2024.]

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Podaci o radu
Naslov (engleski)Viral Inhibition of BAK Promotes Murine Cytomegalovirus Dissemination to Salivary Glands
AutorW. Handke
AutorC. Luig
AutorBranka Popović
AutorAstrid Krmpotić
AutorStipan Jonjić
AutorWolfram Brune
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Apoptosis induction is an important host defense mechanism to control viral infection, which is antagonized by viral proteins. Murine cytomegalovirus m41.1 encodes a viral inhibitor of BAK oligomerization (vIBO) that blocks the mitochondrial apoptosis mediator BAK. However, its importance for viral fitness in vivo has not been investigated. Here, we show that an m41.1-deficient virus attains reduced titers in salivary glands of wild-type but not Bak1(-/-) mice, indicating a requirement of BAK inhibition for optimal dissemination in vivo.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Virology
Brojčani podacivol. 87, br. 6, str. 3592-3596
p-ISSN0022-538X
DOIhttps://doi.org/10.1128/JVI.02657-12
URN:NBNurn:nbn:hr:184:801946
Datum objave publikacije2013-01-09
Datum objave publikacije2013-03-15
URL dokumentahttp://jvi.asm.org/cgi/doi/10.1128/JVI.02657-12
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2018-11-08 10:43:25