prikaz prve stranice dokumenta Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage
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Scientific paper - Original scientific paper
Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage
Collegium antropologicum, 32 - Supplement 2 (2008), 2; 83-87. urn:nbn:hr:184:110558
Bobinac, Dragica; Španjol, Josip; Marinović, Marin; Zoričić Cvek, Sanja; Marić, Ivana; Cicvarić, Tedi; Fučkar, Dora; Markić, Dean; Vojniković, Božidar

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Bobinac, D., Španjol, J., Marinović, M., Zoričić Cvek, S., Marić, I., Cicvarić, T. ... Vojniković, B. (2008). Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage. Collegium antropologicum, 32 - Supplement 2. (2), 83-87. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:110558

Bobinac, Dragica, et al. "Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage." Collegium antropologicum, vol. 32 - Supplement 2, no. 2, 2008, pp. 83-87. https://urn.nsk.hr/urn:nbn:hr:184:110558

Bobinac, Dragica, Josip Španjol, Marin Marinović, Sanja Zoričić Cvek, Ivana Marić, Tedi Cicvarić, Dora Fučkar, Dean Markić and Božidar Vojniković. "Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage." Collegium antropologicum 32 - Supplement 2, no. 2 (2008): 83-87. https://urn.nsk.hr/urn:nbn:hr:184:110558

Bobinac, D., et al. (2008) 'Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage', Collegium antropologicum, 32 - Supplement 2(2), pp. 83-87. Available at: https://urn.nsk.hr/urn:nbn:hr:184:110558 (Accessed 04 December 2024)

Bobinac D, Španjol J, Marinović M, Zoričić Cvek S, Marić I, Cicvarić T, and sur.. Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage. Collegium antropologicum [Internet]. 2008 [cited 2024 December 04];32 - Supplement 2(2):83-87. Available at: https://urn.nsk.hr/urn:nbn:hr:184:110558

D. Bobinac, et al., "Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage", Collegium antropologicum, vol. 32 - Supplement 2, no. 2, pp. 83-87, 2008. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:110558. [Accessed: 04 December 2024]

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Metadata
Title (english)Expression of Bone Morphogenetic Proteins, Cartilage-Derived Morphogenetic Proteins and Related Receptors in Normal and Osteoarthritic Human Articular Cartilage
AuthorDragica Bobinac
AuthorJosip Španjol
AuthorMarin Marinović
AuthorSanja Zoričić Cvek
AuthorIvana Marić
AuthorTedi Cicvarić
AuthorDora Fučkar
AuthorDean Markić
AuthorBožidar Vojniković
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Ophthalmology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Urology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Newborn and adult articular cartilage expresses bone (BMPs) and cartilage derived morphogenetic proteins (CDMPs). These morphogenetic proteins act over membrane receptors (BMPRs). We examined the expression pattern of BMP-7, BMP-3, CDMP-1, CDMP-2 and their receptors in adult normal and osteoarthritic, articular, knee cartilage. Immunostaining was carried out using polyclonal antibodies. The expression of BMP-7,-3, CDMP-1,-2 was detected in all layers of normal articular cartilage with the strongest expression in chondrocytes of the transitional layer. BMP-7 and CDMPs expression decreased in osteoarthritic articular cartilage whereas BMP-3 expression was absent. BMPR-IA and BMPR-II were strongly expressed in both normal and osteoarthritic articular cartilage. BMPR-IB was not expressed in osteoarthritic (OA) cartilage. BMPs and CDMPs with intact signalling play an important role in articular cartilage homeostasis, preventing cartilage degeneration.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium antropologicum
Numberingvol. 32 - Supplement 2, no. 2, pp. 83-87
p-ISSN0350-6134
e-ISSN1848-9486
URN:NBNurn:nbn:hr:184:110558
Publication2008
Document URLhttps://hrcak.srce.hr/34546
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-05-17 12:59:23