prikaz prve stranice dokumenta Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis
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Scientific paper - Review paper
Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis
Archives of Medical Science, 15 (2019), 6; 1365-1374. https://doi.org/10.5114/aoms.2019.89450
Reiner, Željko; Simental-Mendía, Luis; Ruscica, Massimiliano; Katsiki, Niki; Banach, Maciej; Rasadi, Khalid; Jamialahmadi, Tannaz; Sahebkar, Amirhossein

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Reiner, Ž., Simental Mendía, L., Ruscica, M., Katsiki, N., Banach, M., Rasadi, K. ... Sahebkar, A. (2019). Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis. Archives of Medical Science, 15. (6), 1365-1374. doi: 10.5114/aoms.2019.89450

Reiner, Željko, et al. "Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis." Archives of Medical Science, vol. 15, no. 6, 2019, pp. 1365-1374. https://doi.org/10.5114/aoms.2019.89450

Reiner, Željko, Luis Simental Mendía, Massimiliano Ruscica, Niki Katsiki, Maciej Banach, Khalid Rasadi, Tannaz Jamialahmadi and Amirhossein Sahebkar. "Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis." Archives of Medical Science 15, no. 6 (2019): 1365-1374. https://doi.org/10.5114/aoms.2019.89450

Reiner, Ž., et al. (2019) 'Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis', Archives of Medical Science, 15(6), pp. 1365-1374. doi: 10.5114/aoms.2019.89450

Reiner Ž, Simental Mendía L, Ruscica M, Katsiki N, Banach M, Rasadi K, and sur.. Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis. Archives of Medical Science [Internet]. 2019 [cited 2024 November 18];15(6):1365-1374. doi: 10.5114/aoms.2019.89450

Ž. Reiner, et al., "Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis", Archives of Medical Science, vol. 15, no. 6, pp. 1365-1374, 2019. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:112553. [Accessed: 18 November 2024]

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Metadata
Title (english)Pulse wave velocity as a measure of arterial stiffness in patients with familial hypercholesterolemia: a systematic review and meta-analysis
AuthorŽeljko Reiner
AuthorLuis Simental-Mendía
AuthorMassimiliano Ruscica
AuthorNiki Katsiki
AuthorMaciej Banach
AuthorKhalid Rasadi
AuthorTannaz Jamialahmadi
AuthorAmirhossein Sahebkar
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Introduction: The aim of this meta-analysis was to establish whether vascular pulse wave velocity (PWV) as a measure of arterial stiffness is changed in patients with familial hypercholesterolemia (FH). ----- Material and methods: Studies comparing PWV between patients with FH and controls were searched in PubMed-Medline, SCOPUS, Web of Science and Google Scholar databases (up to November 26, 2017). A meta-analysis was conducted using Comprehensive Meta-Analysis V2 software. A random-effects model (using the DerSimonian-Laird method) and the generic inverse variance method were used to compensate for the heterogeneity of studies concerning demographic characteristics and differences in the studies' design. ----- Results: This meta-analysis of 8 studies involving 317 patients with FH and 244 non-FH individuals did not suggest a significantly altered PWV in FH patients versus controls (weighted mean difference (WMD): 0.17 m/s, 95% confidence interval (CI): -0.31, 0.65, p = 0.489; I 2 = 80.15%). The result was robust in the sensitivity analysis and its significance was not influenced after omitting each of the included studies from the meta-analysis. Subanalysis of 6 of these studies which had data on intima-media thickness (IMT) indicated an increased IMT in FH patients when compared with controls (WMD = 0.03 mm, 95% CI: 0.003, 0.06, p = 0.034; I 2 = 48.95%). However, the effect size was sensitive to some of the included studies. ----- Conclusions: This meta-analysis suggests that FH patients do not have significantly altered PWV when compared with normocholesterolemic individuals. However, a subanalysis of studies in which IMT was measured indicated that IMT is increased in FH patients compared with controls.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleArchives of Medical Science
Numberingvol. 15, no. 6, pp. 1365-1374
p-ISSN1734-1922
DOIhttps://doi.org/10.5114/aoms.2019.89450
URN:NBNurn:nbn:hr:184:112553
Publication2019
Document URLhttps://www.termedia.pl/doi/10.5114/aoms.2019.89450
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2022-03-16 15:12:56