prikaz prve stranice dokumenta Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease
  Download
PDF 79.03 KB
Scientific paper - Original scientific paper
Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease
Acta Dermato-Venereologica Supplementum, 211 (2000); 14-16. https://doi.org/10.1080/00015550050500059
Prpić, Larisa; Štrbo, Nataša; Sotošek, Vlatka; Gruber, Franjo; Podack, Eckhard R.; Rukavina, Daniel

Cite this document

Prpić, L., Štrbo, N., Sotošek, V., Gruber, F., Podack, E. R. & Rukavina, D. (2000). Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease. Acta Dermato-Venereologica Supplementum, 211., 14-16. doi: 10.1080/00015550050500059

Prpić, Larisa, et al. "Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease." Acta Dermato-Venereologica Supplementum, vol. 211, 2000, pp. 14-16. https://doi.org/10.1080/00015550050500059

Prpić, Larisa, Nataša Štrbo, Vlatka Sotošek, Franjo Gruber, Eckhard R. Podack and Daniel Rukavina. "Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease." Acta Dermato-Venereologica Supplementum 211 (2000): 14-16. https://doi.org/10.1080/00015550050500059

Prpić, L., et al. (2000) 'Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease', Acta Dermato-Venereologica Supplementum, 211, pp. 14-16. doi: 10.1080/00015550050500059

Prpić L, Štrbo N, Sotošek V, Gruber F, Podack ER, Rukavina D. Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease. Acta Dermato-Venereologica Supplementum [Internet]. 2000 [cited 2024 December 25];211:14-16. doi: 10.1080/00015550050500059

L. Prpić, N. Štrbo, V. Sotošek, F. Gruber, E. R. Podack and D. Rukavina, "Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease", Acta Dermato-Venereologica Supplementum, vol. 211, pp. 14-16, 2000. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:001688. [Accessed: 25 December 2024]

Please login to the repository to save this object to your list.
Metadata
Title (english)Assessment of Perforin Expression in Peripheral Blood Lymphocytes in Psoriatic Patients During Exacerbation of Disease
AuthorLarisa Prpić
AuthorNataša Štrbo
AuthorVlatka Sotošek
AuthorFranjo Gruber
AuthorEckhard R. Podack
AuthorDaniel Rukavina
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Dermatovenerology)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Physiology, Immunology and Pathophxsiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Dermatovenerology
Abstract (english)
There are very few data concerning the role played by cellmediated cytotoxicity, particularly at the molecular level, in the course of psoriasis. Both cytotoxic T lymphocytes (CTL) and natural killer cells contain in their granules the cytolytic protein perforin, a mediator in cell-mediated cytotoxicity reactions. The aim of this study was to analyze perforin expression in various sets and subsets of perforin-positive peripheral blood lymphocytes in 17 patients with chronic psoriasis vulgaris in the exacerbation phase. The results were compared with those of an age- and sex-matched healthy control group (n= 21). Perforin (intracellular antigen) and cell surface antigens were detected using the simultaneous double-staining method. We found a signi®cant increase in perforin (P) expression in the patient group for CTL (CD3+ P+ cells), which are located mostly in the CD8+ population of T lymphocytes (CD8+ P+ ).
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review - international
Publication versionPublished version
Journal titleActa Dermato-Venereologica Supplementum
Numberingvol. 211, pp. 14-16
p-ISSN0365-8341
DOIhttps://doi.org/10.1080/00015550050500059
URN:NBNurn:nbn:hr:184:001688
Publication2000
Document URLhttps://www.medicaljournals.se/acta/content/abstract/10.1080/00015550050500059
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2018-06-28 08:51:23