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Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature
Medica Jadertina, 44 (2015), 3-4; 119-123. urn:nbn:hr:184:511037
Flego, Veljko

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Flego, V. (2015). Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature. Medica Jadertina, 44. (3-4), 119-123. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:511037

Flego, Veljko. "Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature." Medica Jadertina, vol. 44, no. 3-4, 2015, pp. 119-123. https://urn.nsk.hr/urn:nbn:hr:184:511037

Flego, Veljko. "Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature." Medica Jadertina 44, no. 3-4 (2015): 119-123. https://urn.nsk.hr/urn:nbn:hr:184:511037

Flego, V. (2015) 'Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature', Medica Jadertina, 44(3-4), pp. 119-123. Available at: https://urn.nsk.hr/urn:nbn:hr:184:511037 (Accessed 18 December 2024)

Flego V. Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature. Medica Jadertina [Internet]. 2015 January 14 [cited 2024 December 18];44(3-4):119-123. Available at: https://urn.nsk.hr/urn:nbn:hr:184:511037

V. Flego, "Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature", Medica Jadertina, vol. 44, no. 3-4, pp. 119-123, January 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:511037. [Accessed: 18 December 2024]

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Metadata
Title (croatian)Mukoepidermoidni karcinom pluća - prikaz slučaja i pregled literature
Title (english)Mucoepidermoid carcinoma of the lung - case report and literature review
AuthorVeljko Flego
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (croatian)
Mukoepidermoidni karcinom (MEC) rijetki je primarni maligni tumor traheobronhalnoga stabla i obuhvaća 0,1 – 0,2% primarnih karcinoma pluća. Tumor sačinjavaju epitelne stanice, stanice koju izlučuju sluz, te stanice intermedijarnog tipa koje se jednake stanicama koje se javljaju u žlijezdama slinovnicama. Prognoza bolesti ovisi o histološkom stupnju malignosti i može biti loša, naročito u starijih bolesnika. Prikazali smo bolesnicu u dobi od 27 godina, koja je bila subfebrilna četiri mjeseca prije javljanja liječniku. Standardna sumacijska snimka torakalnih organa pokazuje homogeno zasjenjenje promjera 50 mm u gornjem lijevom plućnom polju. Višeslojna kompjutorizirana tomografija (MSCT) prsnoga koša pokazuje lobuliranu formaciju veličine 50 x 27 mm s uključenim hipodenznim zonama, koja se utiskuje u lijevi glavni bronh i opstruira ga. Nisu ustanovljene metastaze medijastinalnih limfnih čvorova, niti drugih organa. Bronhoskopijom se nađe tumor koji opstruira ulaz u lijevi B1 + B2 bronh. Patohistološki i imunohistokemijski nalaz biopsije tumora pokazuje MEC niskoga stupnja malignosti. U bolesnice je učinjena gornja lobektomija lijevoga plućnog krila i medijastinalna limfadenektomija. Makroskopski je u reseciranom lobusu, u lumenu lijevoga glavnog bronha viđen dobro ograničeni, žućkasti tumor, promjera 35 mm. Histološki nalaz tumora jednak je nalazu ranije učinjene biopsije tumora. Tumor se većim dijelom nalazio u lumenu bronha, kroz koji je prodro u okolno plućno tkivo, ali nije zahvatio pleuru. U reseciranim limfnim čvorovima nije bilo stanica tumora. Nikakvo adjuvantno liječenje nije provedeno. 15 mjeseci nakon operacije tumora pluća naša je bolesnica rodila treće zdravo dijete. Nakon 37 mjeseci praćenja od operacije, nema znakova recidiva tumora pluća.
Abstract (english)
Mucoepidermoid carcinoma (MEC) is a rare primary malignancy of the tracheobronchial tree and comprising 0.1 – 0.2% of primary lung cancers. The tumour is composed of epithelial cells, mucus secreting cells and cells of an intermediate type identical to those occurring in the salivary glands. The prognosis depends on the histological grade. We report the case of a 27-year-old woman who was four months sub febrile before referring to a physician. Chest radiography revealed a mass shadow measuring 50 mm in diameter in the left upper lung field. Chest CT showed a lobulated mass shadow measuring 50 x 27 mm in which there were hypo dense zones. The tumour was pressed into the left main bronchus, and was obstructing it. No mediastinal lymph node metastasis or other organ metastases were observed. Bronchoscopy revealed a tumour obstructing the entry of left B1+2 bronchus. Pathohistological and immunohistochemical findings of tumour forceps biopsy lead to diagnosis of low-grade MEC. The patient underwent left upper lobe resection and mediastinal lymphadenectomy. Macroscopic findings showed a yellowish well-confined tumour node 35 mm in diameter in the lumen of the main bronchus. The tumour tissue was mainly located in the lumen of the bronchus, and penetrated the wall of the bronchus and entered in the underlying lung tissue. The tumour did not affect the pleura. There were no tumour cells in the resected lymph nodes. No adjuvant treatment was administered. Fifteen months after surgery she gave birth to a third healthy son. The patient remains in remission after 37 months of follow-up from tumour resection.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedica Jadertina
Numberingvol. 44, no. 3-4, pp. 119-123
p-ISSN0351-0093
URN:NBNurn:nbn:hr:184:511037
Publication2015-01-14
Document URLhttp://hrcak.srce.hr/133155
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-08-03 06:51:43