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Scientific paper - Case study
Prikaz slučaja sekundarnog angiosarkoma dojke
Medicina Fluminensis, 52 (2016), 3; 421-423. https://doi.org/10.21860/52;3_421
Mustać, Elvira; Carović, Franjo; Aničić, Josip; Tomasić, Matea; Beram, Lucija

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Mustać, E., Carović, F., Aničić, J., Tomasić, M. & Beram, L. (2016). Prikaz slučaja sekundarnog angiosarkoma dojke. Medicina Fluminensis, 52. (3), 421-423. doi: 10.21860/52;3_421

Mustać, Elvira, et al. "Prikaz slučaja sekundarnog angiosarkoma dojke." Medicina Fluminensis, vol. 52, no. 3, 2016, pp. 421-423. https://doi.org/10.21860/52;3_421

Mustać, Elvira, Franjo Carović, Josip Aničić, Matea Tomasić and Lucija Beram. "Prikaz slučaja sekundarnog angiosarkoma dojke." Medicina Fluminensis 52, no. 3 (2016): 421-423. https://doi.org/10.21860/52;3_421

Mustać, E., et al. (2016) 'Prikaz slučaja sekundarnog angiosarkoma dojke', Medicina Fluminensis, 52(3), pp. 421-423. doi: 10.21860/52;3_421

Mustać E, Carović F, Aničić J, Tomasić M, Beram L. Prikaz slučaja sekundarnog angiosarkoma dojke. Medicina Fluminensis [Internet]. 2016 September 01 [cited 2024 November 14];52(3):421-423. doi: 10.21860/52;3_421

E. Mustać, F. Carović, J. Aničić, M. Tomasić and L. Beram, "Prikaz slučaja sekundarnog angiosarkoma dojke", Medicina Fluminensis, vol. 52, no. 3, pp. 421-423, September 2016. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:698259. [Accessed: 14 November 2024]

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Metadata
Title (croatian)Prikaz slučaja sekundarnog angiosarkoma dojke
Title (english)Case report of the secondary breast angiosarcoma
AuthorElvira Mustać
AuthorFranjo Carović
AuthorJosip Aničić
AuthorMatea Tomasić
AuthorLucija Beram
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of General Pathology and Pathological Anatomy)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Pathology
Abstract (croatian)
Cilj: Sekundarni angiosarkom dojke rijetka je ali ozbiljna dugoročna komplikacija karcinoma dojke kod pacijenata koji su liječeni poštednim kirurškim zahvatom i radioterapijom. Prikazan je slučaj pacijentice kojoj se sekundarni angiosarkom pojavio sedam godina nakon radioterapije uz naglasak na ulogu pažljivog histološkog pregleda tih tumora. Prikaz slučaja: Pacijentici staroj 66 godina kojoj je 2006. godine dijagnosticiran invazivni duktalni karcinom dojke učinjen je konzervativni kirurški zahvat i odstranjen je limfni čvor čuvar (pT1c, pN0). Postoperativni tretman uključivao je radioterapiju i endokrinu terapiju. Sedam godina nakon radioterapije, 2013. godine pacijentica je primijetila purpurno crveno mjesto na koži u ozračenom području desne dojke. Patohistološka dijagnoza promjene je angiosarkom. Zaključak: Razvoj sekundarnog angiosarkoma dojke povezan je s radioterapijom (RIA) i kroničnim limfedemom (Stewart-Treves sindrom nakon latentnog perioda od 4 do 8 godina). Zbog njegove rijetkosti i naizgled bezopasne prezentacije, jer se često radi o bezbolnoj promjeni nalik modrici na koži, pacijenti i liječnici često zanemaruju početne simptome, što vodi kasnom postavljanju dijagnoze. U vrijeme postavljanja dijagnoze pacijenti često imaju lokaliziranu bolest koja je ograničena na dojku, ali s multifokalnim rastom.
Abstract (english)
Aim: Secondary angiosarcoma of the breast is a rare but severe long-term complication of breast carcinoma treated with breast-conserving surgery and radiotherapy. We report here a case which occurred seven years after radiotherapy to highlight the awareness of the disease and the role of careful histological evaluation of these tumours. Case report: The 66-year-old patient with right breast infiltrating ductal carcinoma in December 2006. She underwent conservative breast surgery and sentinel lymph node dissection (pT1c, pN0). Her postoperative treatment included radiotherapy and endocrine therapy. Seven years after the radiotherapy (2013), the patient noticed a purplish spot in the skin of the previously irradiated field of the right breast. The histopathology reviewed a diagnosis of angiosarcoma. Conclusion: The development of secondary angiosarcoma has been linked to radiotherapy (RIA) and chronic lymphedema (Stewart–Treves syndrome) after median latency period of 4–8 years. Because of their rarity and seemingly harmless presentation, frequently comprising painless and bruise like skin lesions, both patients and doctors often neglect the initial symptoms and diagnosis is delayed.
Keywords (croatian)
Keywords (english)
Languagecroatian
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleMedicina Fluminensis
Numberingvol. 52, no. 3, pp. 421-423
p-ISSN0025-7729
DOIhttps://doi.org/10.21860/52;3_421
URN:NBNurn:nbn:hr:184:698259
Publication2016-09-01
Document URLhttp://hrcak.srce.hr/163938
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-04-20 16:48:02