Access restricted to higher education institution's students and staff
master's thesis
Manifestacije infekcije virusom humane imunodeficijencije na oralnoj sluznici

Valentina Vidmar (2014)
Metadata
TitleManifestacije infekcije virusom humane imunodeficijencije na oralnoj sluznici
AuthorValentina Vidmar
Mentor(s)Irena Glažar (thesis advisor)
Abstract
HIV je jedna od najzastupljenijih infekcija imunosnog sustava čovjeka današnjice. Virus pomoću enzima reverzne transkriptaze prevodi svoju RNK na DNK domaćina te tako inficira stanicu. Prenosi se preko tjelesnih tekućina, najviše putem krvi, spolnog kontakta te s majke na dijete pri porodu ili tijekom dojenja. Klinički tijek bolesti je dugotrajan, a započinje kao sindrom sličan mononukleozi s glavoboljom, vrućicom, mialgijom, slabosti i sličnim blagim simptomima da bi zatim ušla u period latencije koji može potrajati i više od 10 godina. Nakon toga počinju se javljati sve brojnije i teže kronične infekcije kao znak propadanja imunosnog sustava. Kod dentalnog liječenja bolesnika s HIV-om najvažnije je prepoznati promjene uske vezane s infekcijom te pokušati educirati bolensika o pravilnom održavanju higijene. Lezije oralne sluznice usko povezane s HIV-om su kandidijaza (eritematozna, atrofična, pseudomembranozna, angularni chielitis), vlasasta leukoplakija, Kaposijev sarkom, non-Hodgkin limfom te parodontne bolesti (linearni gingivni eritem, ulcerozni nekrotizirajući gingivitis i parodontitis). Često se u takvih bolesnika javljaju i kronične infekcije HSV-om, HPV-om, rekurentne aftozne ulceracije te problemi sa suhoćom sune šupljine. Iako se pristup doktora dentalne medicine bolesniku oboljelom od HIV-a ne bi trebao razlikovati od pristupa zdravom pojedincu, ne smijemo zanemariti broj krvnih pločica i leukocita koji se s progresijom bolesti smanjuju kao i da moramo razmisliti o profilaksi kod određenih zahvata. Veoma su bitne mjere opreza i zaštite liječnika i ostalog osoblja u ordinaciji kao i poštivanje protokola u slučaju ubodnog incidenta ili kontakta s krvlju zaražene osobe.
KeywordsHIV infections Oral Manifestations
GranterSveučilište u Rijeci
Medicinski fakultet
Lower level organizational unitsKatedra za oralnu medicinu i parodontologiju
PlaceRijeka
StateCroatia
Scientific field, discipline, subdisciplineBIOMEDICINE AND HEALTHCARE
Dental Medicine
Oral Medicine
Study programme typeuniversity
Study levelintegrated undergraduate and graduate
Study programmeDental Medicine
Academic title abbreviationdr. med. dent.
Genremaster's thesis
Language Croatian
Defense date2014
Parallel abstract (English)
HIV is one of the most common infections of the immune system in human kind today. The virus uses it's enzyme know as reverse transcriptaze to translate it's RNA to the host's cell DNA. The disease is transmitted mainly through body fluids, especially blood, during intercourse and from mother to child during birth or breastfeeding, The clinical course of the disease itself is very extended; it starts as a mononucleosis like syndrome with headache, mialgia, weakness and similar mild symptoms and that is when the infection enter it's latent asymptomatic phase which can last up to 10 years. After this period, more and more chronic and persistent infections start to appear as a sign of a deteriorating immune system. When it comes to the dental treatment of a HIV patient, it's essential to recognize the oral cavity lesions closely related to the disease and to instruct the patients how to maintain an immaculate oral hygene which can lessen or even prevent these problems. The lesions strongly associated with HIV are : Candidiasis (erythematosus and pseudomembraneous), hairy leukoplakia, Kaposi's sarcoma, non-Hodgkin's lymphoma and periodontal disease (linear gingival erythema, necrotizing ulcerative gingivitis/periodontitis). In those patients chronic infections like HSV, HPV, recurrent aphtous ulcers and xerostomia are also a very common problem. Although the approach of the doctor of dental medicine towards a healthy individual or HIV patient should not be different, it's very important to cosider the patient's blood cell count, especially leukocytes and trombocytes. Similarly, the proper use of prophylaxis when needed is crucial. Precaution and safety measures are essential to protect not only the therapist and his staff but as well every other patient. Also, every doctor must be well informed of the protocol in case of contact with a contaminated needle or infected blood.
Parallel keywords (Croatian)HIV infekcije Oralna sluznica - upala
Resource typetext
Access conditionAccess restricted to higher education institution's students and staff
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:184:518370
CommitterBosa Licul