prikaz prve stranice dokumenta Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease
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Scientific paper - Case study
Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease
Croatian medical journal, 44 (2003), 4; 485-488. urn:nbn:hr:184:421725
Flego, Veljko; Radojčić Badovinac, Anđelka; Pleše, Vika; Kapović, Miljenko; Beg-Zec, Zlata; Zaputović, Luka

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Flego, V., Radojčić Badovinac, A., Pleše, V., Kapović, M., Beg Zec, Z. & Zaputović, L. (2003). Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease. Croatian medical journal, 44. (4), 485-488. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:421725

Flego, Veljko, et al. "Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease." Croatian medical journal, vol. 44, no. 4, 2003, pp. 485-488. https://urn.nsk.hr/urn:nbn:hr:184:421725

Flego, Veljko, Anđelka Radojčić Badovinac, Vika Pleše, Miljenko Kapović, Zlata Beg Zec and Luka Zaputović. "Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease." Croatian medical journal 44, no. 4 (2003): 485-488. https://urn.nsk.hr/urn:nbn:hr:184:421725

Flego, V., et al. (2003) 'Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease', Croatian medical journal, 44(4), pp. 485-488. Available at: https://urn.nsk.hr/urn:nbn:hr:184:421725 (Accessed 05 November 2024)

Flego V, Radojčić Badovinac A, Pleše V, Kapović M, Beg Zec Z, Zaputović L. Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease. Croatian medical journal [Internet]. 2003 [cited 2024 November 05];44(4):485-488. Available at: https://urn.nsk.hr/urn:nbn:hr:184:421725

V. Flego, A. Radojčić Badovinac, V. Pleše, M. Kapović, Z. Beg Zec and L. Zaputović, "Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease", Croatian medical journal, vol. 44, no. 4, pp. 485-488, 2003. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:184:421725. [Accessed: 05 November 2024]

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Metadata
Title (english)Malignancy Risk in Patient with Neurofibromatosis and Autosomal Dominant Polycystic Kidney Disease
AuthorVeljko Flego
AuthorAnđelka Radojčić Badovinac
AuthorVika Pleše
AuthorMiljenko Kapović
AuthorZlata Beg-Zec
AuthorLuka Zaputović
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Biology and Medical Genetics)
Author's institutionUniversity of Rijeka
Faculty of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Cancer appearance in some inherited diseases depends on the interactions with other genes. Lung cancer is rare in neurofibromatosis and has not been reported in Caucasian population. In this paper, we present the case of lung adenocarcinoma in a patient with neurofibromatosis, pseudoarthrosis of tibia, and autosomal dominant polycystic kid - ney disease. Cytogenetic analysis of the pleural effusion showed chaotic cleavage and constitutional inversion of chro- mosome 9, transmitted from the mother. Family investiga tion revealed two autosomal dominant diseases, neuro- fibromatosis and polycystic kidney disease in the same family. These findings suggest that the second autosomal dominant disease in the family and inversion of chromosome 9 contributed to the severity of neurofibromatosis and pa- tient’s risk to malignancies.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian medical journal
Numberingvol. 44, no. 4, pp. 485-488
p-ISSN0353-9504
e-ISSN1332-8166
URN:NBNurn:nbn:hr:184:421725
Publication2003
Document URLhttp://www.cmj.hr/2003/44/4/12950155.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-08-01 10:59:07