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master's thesis
USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD)
2015. urn:nbn:hr:184:327364
Ratković, Tea
University of Rijeka
Faculty of Medicine
Department of Surgery

Cite this document

Ratković, T. (2015). USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD) (Master's thesis). Rijeka: University of Rijeka, Faculty of Medicine. Retrieved from https://urn.nsk.hr/urn:nbn:hr:184:327364

Ratković, Tea. "USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD)." Master's thesis, University of Rijeka, Faculty of Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:184:327364

Ratković, Tea. "USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD)." Master's thesis, University of Rijeka, Faculty of Medicine, 2015. https://urn.nsk.hr/urn:nbn:hr:184:327364

Ratković, T. (2015). 'USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD)', Master's thesis, University of Rijeka, Faculty of Medicine, accessed 24 February 2025, https://urn.nsk.hr/urn:nbn:hr:184:327364

Ratković T. USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD) [Master's thesis]. Rijeka: University of Rijeka, Faculty of Medicine; 2015 [cited 2025 February 24] Available at: https://urn.nsk.hr/urn:nbn:hr:184:327364

T. Ratković, "USPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD)", Master's thesis, University of Rijeka, Faculty of Medicine, Rijeka, 2015. Available at: https://urn.nsk.hr/urn:nbn:hr:184:327364

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Metadata
TitleUSPOREDBA VENSKOG I PROTETSKOG PRESATKA PRI FEMOROPOPLITEALNOM PREMOŠTENJU (PAD)
AuthorTea Ratković
MentorMiljenko Kovačević (mentor)
GranterUniversity of Rijeka
Faculty of Medicine
(Department of Surgery)
Rijeka
Defense date and country2015, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Surgery
Abstract
Periferna arterijska bolest (PAD) je uzrokovana sistemskom aterosklerozom, a manifestira se različitim simptomima i znakovima koji ukazuju na ishemiju ekstremiteta. Prevalencija bolesti raste progresivno s dobi. Glavni čimbenici rizika nastanka periferne arterijske bolesti su dob, spol, rasa, pušenje, šećerna bolest, arterijska hipertenzija, hiperlipidemija, hiperhomocisteinemija. Simptomi periferne arterijske bolesti donjih ekstremiteta su intermitentne klaudikacije, bolovi u mirovanju te ishemijske ulceracije i gangrene. Periferna arterijska bolest često dovodi do nastanka lezija u femoropoplitealnom segmentu. U klasifikaciji lezija femoropoplitealnog područja koriste se TASC smjernice. TASC smjernice su utemeljene na morfološkim karakteristikama lezija te sadrže preporuke za početno liječenje. Liječenje pacijenata ovisi o težini simptoma, a kod asimptomatskih bolesnika potrebna je redovita kontrola i korekcija rizičnih čimbenika. Od farmakoloških lijekova najčešće se koriste antihipertenzivi, antiagregacijski lijekovi, statini, vazodilatatori, prostaglandini, inhibitori fosfodiesteraze te antagonisti 5-HT2 receptora. Endovaskularna metoda se koristi u liječenju stenoza ili kratkih okluzija femoropoplitealnog područja te ona predstavlja alternativnu metodu revaskularizacije kod pacijenata koji zbog komorbiditeta ne mogu biti podvrgnuti angiokirurškoj metodi premoštenja. Angiokirurška metoda premoštenja pomoću presatka i dalje predstavlja zlatni standard u liječenju dugih lezija femoropoplitealnog područja. Pri femoropoplitealnom premoštenju koriste se venski i protetski (PTFE, Dacron) presadci. Protetski presadci predstavljaju alternativnu metodu, no autologna vena safena i dalje predstavlja prvi izbor pri premoštenju.
Abstract (english)
Peripheral arterial disease (PAD) is caused by systemic atherosclerosis, manifested by various symptoms and signs suggestive of extremity ischemia. The prevalence of the disease increases progressively with age. The main risk factors of peripheral arterial disease are age, sex, race, smoking, diabetes, hypertension, hyperlipidemia, hyperhomocysteinemia. Symptoms of peripheral arterial disease of the lower extremities are intermittent claudication, pain at rest and ischemic ulceration and gangrene. Peripheral arterial disease often leads to the formation of lesions in femoro- popliteal area. For classification of lesions in femoropopliteal area are used TASC guidelines. TASC guidelines are based on morphological characteristics of the lesion and contain recommendations for initial treatment. Treatment of patients depending on the severity of symptoms, and asymptomatic patients require regular control and correction of risk factors. Pharmacological drugs commonly used are antihypertensive agents, antiplatelet agents, statins, vasodilators, prostaglandins, phosphodiesterase inhibitors and antagonists of 5-HT2 receptors. Endovascular methods is used in treating stenosis or occlusion of short femoropopliteal area and it is an alternative method of revascularization in patients that because of comorbidity can't be expose to bypass method. Method using the bypass graft is still the gold standard in the treatment of long lesions in femoro-popliteal area. In femoro-popliteal bypass we can use a venous and prosthetic (PTFE, Dacron) grafts. Prosthetic grafts represent an alternative method, but autologous saphenous vein is still the first choice for bypass.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:184:327364
Study programmeTitle: Medicine
Study programme type: university
Study level: integrated undergraduate and graduate
Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2016-02-11 10:40:55