prikaz prve stranice dokumenta Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases
  Preuzmi
PDF 1.66 MB
Znanstveni rad - Pregledni rad
Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases
Gastrointestinal Disorders, 7 (2025), 2; 28. https://doi.org/10.3390/gidisord7020028
Jagodić, Ana; Kršek, Antea; Schleicher, Lou Marie Salomé; Batičić, Lara

Citirajte ovaj rad

Jagodić, A., Kršek, A., Schleicher, L. M. S. i Batičić, L. (2025). Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases. Gastrointestinal Disorders, 7. (2). doi: 10.3390/gidisord7020028

Jagodić, Ana, et al. "Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases." Gastrointestinal Disorders, vol. 7, br. 2, 2025. https://doi.org/10.3390/gidisord7020028

Jagodić, Ana, Antea Kršek, Lou Marie Salomé Schleicher i Lara Batičić. "Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases." Gastrointestinal Disorders 7, br. 2 (2025). https://doi.org/10.3390/gidisord7020028

Jagodić, A., et al. (2025) 'Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases', Gastrointestinal Disorders, 7(2). doi: 10.3390/gidisord7020028

Jagodić A, Kršek A, Schleicher LMS, Batičić L. Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases. Gastrointestinal Disorders [Internet]. 02.04.2025. [pristupljeno 08.04.2025.];7(2). doi: 10.3390/gidisord7020028

A. Jagodić, A. Kršek, L. M. S. Schleicher i L. Batičić, "Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases", Gastrointestinal Disorders, vol. 7, br. 2, Travanj 2025. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:950134. [Citirano: 08.04.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:950134
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)Microbiome Dysbiosis as a Driver of Neurodegeneration: Insights into Alzheimer’s and Parkinson’s Diseases
AutorAna Jagodić
AutorAntea Kršek
AutorLou Marie Salomé Schleicher
AutorLara Batičić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Microbiome dysbiosis—an imbalance in gut microbial communities—has emerged as a critical factor in the pathogenesis of neurological disorders, particularly Alzheimer’s and Parkinson’s diseases. This review examines the role of gut microbiota in neurodegeneration, emphasizing how dysbiosis disrupts gut–brain communication through mechanisms such as impaired gut permeability, systemic inflammation, and neuroinflammation. The gastrointestinal and central nervous systems interact bidirectionally, with microbial metabolites like short-chain fatty acids playing a pivotal role in maintaining gut and brain health. Dysbiotic shifts in microbial composition can compromise the blood–brain barrier, enabling inflammatory molecules to alter brain biochemistry and potentially accelerate neurodegenerative processes. Additionally, this review explores therapeutic strategies—including probiotics, prebiotics, and dietary modifications—designed to restore microbial balance, reduce neuroinflammation, and slow disease progression. Further research is essential to refine microbiome-targeted therapies and fully elucidate their potential in managing neurodegenerative diseases.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaGastrointestinal Disorders
Brojčani podacivol. 7, br. 2, 28
e-ISSN2624-5647
DOIhttps://doi.org/10.3390/gidisord7020028
URN:NBNurn:nbn:hr:184:950134
Datum objave publikacije2025-04-02
URL dokumentahttps://www.mdpi.com/2624-5647/7/2/28
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2025-04-03 06:58:33