prikaz prve stranice dokumenta The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair
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The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair
International Journal of Molecular Sciences, 25 (2024), 7; 3882. https://doi.org/10.3390/ijms25073882
Volarić, Darian; Žauhar, Gordana; Chen, Jie; Jerbić Radetić, Ana Terezija; Omrčen, Hrvoje; Raič, Antonio; Pirović, Roko; Cvijanović Peloza, Olga

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Volarić, D., Žauhar, G., Chen, J., Jerbić Radetić, A. T., Omrčen, H., Raič, A. ... Cvijanović Peloza, O. (2024). The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair. International Journal of Molecular Sciences, 25. (7). doi: 10.3390/ijms25073882

Volarić, Darian, et al. "The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair." International Journal of Molecular Sciences, vol. 25, br. 7, 2024. https://doi.org/10.3390/ijms25073882

Volarić, Darian, Gordana Žauhar, Jie Chen, Ana Terezija Jerbić Radetić, Hrvoje Omrčen, Antonio Raič, Roko Pirović i Olga Cvijanović Peloza. "The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair." International Journal of Molecular Sciences 25, br. 7 (2024). https://doi.org/10.3390/ijms25073882

Volarić, D., et al. (2024) 'The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair', International Journal of Molecular Sciences, 25(7). doi: 10.3390/ijms25073882

Volarić D, Žauhar G, Chen J, Jerbić Radetić AT, Omrčen H, Raič A, i sur.. The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair. International Journal of Molecular Sciences [Internet]. 30.03.2024. [pristupljeno 03.12.2024.];25(7). doi: 10.3390/ijms25073882

D. Volarić, et al., "The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair", International Journal of Molecular Sciences, vol. 25, br. 7, Ožujak 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:313128. [Citirano: 03.12.2024.]

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Podaci o radu
Naslov (engleski)The Effect of Low-Intensity Pulsed Ultrasound on Bone Regeneration and the Expression of Osterix and Cyclooxygenase-2 during Critical-Size Bone Defect Repair
AutorDarian Volarić
AutorGordana Žauhar
AutorJie Chen
AutorAna Terezija Jerbić Radetić
AutorHrvoje Omrčen
AutorAntonio Raič
AutorRoko Pirović
AutorOlga Cvijanović Peloza
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Low-intensity pulsed ultrasound (LIPUS) is a form of ultrasound that utilizes low-intensity pulsed waves. Its effect on bones that heal by intramembranous ossification has not been sufficiently investigated. In this study, we examined LIPUS and the autologous bone, to determine their effect on the healing of the critical-size bone defect (CSBD) of the rat calvaria. The bone samples underwent histological, histomorphometric and immunohistochemical analyses. Both LIPUS and autologous bone promoted osteogenesis, leading to almost complete closure of the bone defect. On day 30, the bone volume was the highest in the autologous bone group (20.35%), followed by the LIPUS group (19.12%), and the lowest value was in the control group (5.11%). The autologous bone group exhibited the highest intensities of COX-2 (167.7 ± 1.1) and Osx (177.1 ± 0.9) expression on day 30. In the LIPUS group, the highest intensity of COX-2 expression was found on day 7 (169.7 ±1.6) and day 15 (92.7 ± 2.2), while the highest Osx expression was on day 7 (131.9 ± 0.9). In conclusion, this study suggests that LIPUS could represent a viable alternative to autologous bone grafts in repairing bone defects that are ossified by intramembranous ossification.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Molecular Sciences
Brojčani podacivol. 25, br. 7, 3882
e-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms25073882
URN:NBNurn:nbn:hr:184:313128
Datum objave publikacije2024-03-30
ProjektŠifra: uniri-biomed-18-280
Naziv (hrvatski): Reparacija i imunosni odgovor koštanog tkiva nakon primjene novog biomaterijala te imunosni odgovor mekog tkiva na Jason membranu u štakoru
Naziv (engleski): Reparation and immune response of bone tissue after applying new biomaterial and immune response of soft tissue on Jason® membrane in rat
Voditelj: Olga Peloza
Pravna nadležnost: Hrvatska
Financijer: NadSve
Linija financiranja: Nema
URL dokumentahttps://www.mdpi.com/1422-0067/25/7/3882
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-04-02 10:20:14