prikaz prve stranice dokumenta Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease
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Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease
International Journal of Cardiology, 161 (2012), 3; 156-159. https://doi.org/10.1016/j.ijcard.2012.05.044
Marčun, Robert; Šustić, Alan; Brguljan, Pika Mesko; Kadivec, Saša; Farkaš, Jerneja; Kosnik, Mitja; Coats, Andrew J. Stewart; Anker, Stefan D.; Lainscak, Mitja

Citirajte ovaj rad

Marčun, R., Šustić, A., Brguljan, P. M., Kadivec, S., Farkaš, J., Kosnik, M. ... Lainscak, M. (2012). Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease. International Journal of Cardiology, 161. (3), 156-159. doi: 10.1016/j.ijcard.2012.05.044

Marčun, Robert, et al. "Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease." International Journal of Cardiology, vol. 161, br. 3, 2012, str. 156-159. https://doi.org/10.1016/j.ijcard.2012.05.044

Marčun, Robert, Alan Šustić, Pika Mesko Brguljan, Saša Kadivec, Jerneja Farkaš, Mitja Kosnik, Andrew J. Stewart Coats, Stefan D. Anker i Mitja Lainscak. "Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease." International Journal of Cardiology 161, br. 3 (2012): 156-159. https://doi.org/10.1016/j.ijcard.2012.05.044

Marčun, R., et al. (2012) 'Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease', International Journal of Cardiology, 161(3), str. 156-159. doi: 10.1016/j.ijcard.2012.05.044

Marčun R, Šustić A, Brguljan PM, Kadivec S, Farkaš J, Kosnik M, i sur.. Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease. International Journal of Cardiology [Internet]. 11.2012. [pristupljeno 06.05.2024.];161(3):156-159. doi: 10.1016/j.ijcard.2012.05.044

R. Marčun, et al., "Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease", International Journal of Cardiology, vol. 161, br. 3, str. 156-159, Studeni 2012. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:603111. [Citirano: 06.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:603111
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Naslov (engleski)Cardiac biomarkers predict outcome after hospitalisation for an acute exacerbation of chronic obstructive pulmonary disease
AutorRobert Marčun
AutorAlan Šustić
AutorPika Mesko Brguljan
AutorSaša Kadivec
AutorJerneja Farkaš
AutorMitja Kosnik
AutorAndrew J. Stewart Coats
AutorStefan D. Anker
AutorMitja Lainscak
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Purpose: In chronic obstructive pulmonary disease (COPD), cardiovascular system is involved but less is known about role of specific cardiac biomarkers. We aimed to investigate associations between N-terminal pro B-type natriuretic peptide (NT-proBNP) and troponin T during hospitalisation with 6-month outcome. Methods: This was a prospective study conducted in consecutive patients hospitalized for an acute exacerbation of COPD. On admission, and at discharge, NT-proBNP and troponin T were measured, and echocardiography was performed. Hospitalisations and mortality were recorded for 6 months after discharge. Results: We included 127 patients (70 ± 10 years, 70% men, GOLD III/IV 87%). Left ventricular dysfunction was detected in 70 (55%) patients and diastolic dysfunction was the most common type (53 patients-42%). NT-proBNP and troponin T were elevated on admission in 60% and 36%, and at discharge in 28% and 19% of patients. During follow-up, 53 (42%) patients were hospitalized and 17 (13%) patients died. In Kaplan Meier analysis of survival curves, NT-proBNP on admission distinguished between deceased and surviving patients (p = 0.011) whilst troponin T at discharge separated hospitalized and non-hospitalized patients (p = 0.017). The adjusted Cox proportional hazard model confirmed these findings: discharge troponin T predicted hospitalisations (hazard ratio 2.89, 95% confidence interval 1.13-7.36) and admission NT-proBNP predicted mortality (hazard ratio 4.20, 95% confidence interval 1.07-14.01). Conclusions: Elevated NT-proBNP at discharge and troponin T on admission predict outcome in patients hospitalized for an acute exacerbation of COPD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Cardiology
Brojčani podacivol. 161, br. 3, str. 156-159
p-ISSN0167-5273
DOIhttps://doi.org/10.1016/j.ijcard.2012.05.044
URN:NBNurn:nbn:hr:184:603111
Datum objave publikacije2012-11
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S0167527312006560
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
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Datum i vrijeme pohrane2023-11-02 09:34:58