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Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis
Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences, 59 (2023), 2; 241-250. https://doi.org/10.20471/dec.2023.59.02.07
Nadalin, Sergej; Peitl, Vjekoslav; Karlović, Dalibor; Huskić, Sara; Zatković, Lena; Buretić-Tomljanović, Alena

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Nadalin, S., Peitl, V., Karlović, D., Huskić, S., Zatković, L. i Buretić Tomljanović, A. (2023). Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis. Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences, 59. (2), 241-250. doi: 10.20471/dec.2023.59.02.07

Nadalin, Sergej, et al. "Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis." Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences, vol. 59, br. 2, 2023, str. 241-250. https://doi.org/10.20471/dec.2023.59.02.07

Nadalin, Sergej, Vjekoslav Peitl, Dalibor Karlović, Sara Huskić, Lena Zatković i Alena Buretić Tomljanović. "Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis." Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences 59, br. 2 (2023): 241-250. https://doi.org/10.20471/dec.2023.59.02.07

Nadalin, S., et al. (2023) 'Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis', Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences, 59(2), str. 241-250. doi: 10.20471/dec.2023.59.02.07

Nadalin S, Peitl V, Karlović D, Huskić S, Zatković L, Buretić Tomljanović A. Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis. Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences [Internet]. 2023. [pristupljeno 06.05.2024.];59(2):241-250. doi: 10.20471/dec.2023.59.02.07

S. Nadalin, V. Peitl, D. Karlović, S. Huskić, L. Zatković i A. Buretić Tomljanović, "Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis", Archives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences, vol. 59, br. 2, str. 241-250, 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:502393. [Citirano: 06.05.2024.]

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Podaci o radu
Naslov (engleski)Correlations Between Clinical and Metabolic Variables and Smoking among Antipsychotic- Naïve First-Episode and Nonadherent Chronic Patients with Psychosis
AutorSergej Nadalin
AutorVjekoslav Peitl
AutorDalibor Karlović
AutorSara Huskić
AutorLena Zatković
AutorAlena Buretić-Tomljanović
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Psihijatrija
Sažetak (engleski)
An interaction between smoking and antipsychotic medications could potentially affect treatment efficacy and promote metabolic side effects. We investigated the contribution of smoking status towards Positive and Negative Syndrome Scale (PANSS) scores and metabolic syndrome- related parameters (plasma lipid and glucose concentrations, and body mass index) among two groups of unmedicated patients with psychosis from the Croatian population: antipsychotic-naïve first-episode patients and nonadherent chronic patients. Previous data are inconsistent regarding the effects of smoking on clinical psychopathology among antipsychotic-naïve or minimally medicated patients with first-episode psychosis, and no studies have examined the potential influence of smoking on clinical psychopathology and metabolic parameters among nonadherent patients with chronic psychosis. Information about smoking status and antipsychotic nonadherence was obtained via auto-anamnestic and hetero-anamnestic information. PANSS data were obtained while patients were in a psychotic state during the illness requiring hospitalization. Plasma total cholesterol, LDL cholesterol, HDL cholesterol (HDL- c), triglyceride, and glucose levels were determined after a 12-hour fasting period. Compared with non-smoking antipsychotic-naïve first-episode individuals, antipsychotic-naïve smokers exhibited significantly lower depression factor scores, and significantly higher triglyceride levels and triglyceride/HDL- c ratio (p < 0.05). Compared with non-smoking nonadherent chronic individuals, nonadherent smokers exhibited significantly lower negative symptoms and negative factor scores, and lower HDL- c levels. Contributions of smoking to clinical and metabolic parameters ranged from ~ 3.4 % to 10 %. Our present results indicated that smoking may be associated with less severe clinical psychopathology, and with increased risk for metabolic abnormalities, among unmedicated patients with first-episode psychosis and chronic psychosis.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaArchives of Psychiatry Research : An International Journal of Psychiatry and Related Sciences
Brojčani podacivol. 59, br. 2, str. 241-250
p-ISSN2671-1079
e-ISSN2671-2008
DOIhttps://doi.org/10.20471/dec.2023.59.02.07
URN:NBNurn:nbn:hr:184:502393
Datum objave publikacije2023
URL dokumentahttps://hrcak.srce.hr/304154
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Dijeli pod istim uvjetima 4.0 međunarodna (CC BY-NC-SA 4.0)
Datum i vrijeme pohrane2023-08-16 09:02:11