Introduction: Comprehensive sexuality education is an important tool in public health and in the promotion of sexual health, but it is poorly represented in everyday education. Subjects and methods: 135 students participated in the research, of which 47 were men and 88 were women. The interviewees were final year students of two Pula secondary schools – Gimnazija Pula and Medicinska škola Pula. The questionnaire method was chosen for the method of data collection due to its simplicity and anonymity of respondents. Results: The participants showed that secondary school knowledge about sexuality topics is insufficient. Knowledge about contraception is deficient, and it is not possible to determine with certainty the effectiveness of certain types of contraception among high school students, since the correct use of certain methods cannot be guaranteed. The use of contraceptive methods itself is also poorly expressed, and there are no good educational methods to try to solve this problem. They seek information about issues and problems that young people face from their peers and on the Internet, two sources that can be full of unverified information. According to the participants, CSE is not implemented in its full program, but high school students believe that it is very important to include this form of education in the education curriculum. Conclusion: Although the knowledge itself and the application of that knowledge is deficient, the most important result of this study is the high interest shown by high school students in teaching CSE; according to their opinion, education should start already in the upper grades of primary school and should be carried out by medical professionals.