prikaz prve stranice dokumenta Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy
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Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy
American Journal of Reproductive Immunology, 64 (2010); 347-358. https://doi.org/10.1111/j.1600-0897.2010.00844.x
Laškarin, Gordana; Redžovic, Arnela; Vukelić, Petar; Veljković, Danijela; Gulić, Tamara; Haller, Herman; Rukavina, Daniel

Citirajte ovaj rad

Laškarin, G., Redžovic, A., Vukelić, P., Veljković, D., Gulić, T., Haller, H. i Rukavina, D. (2010). Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy. American Journal of Reproductive Immunology, 64., 347-358. doi: 10.1111/j.1600-0897.2010.00844.x

Laškarin, Gordana, et al. "Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy." American Journal of Reproductive Immunology, vol. 64, 2010, str. 347-358. https://doi.org/10.1111/j.1600-0897.2010.00844.x

Laškarin, Gordana, Arnela Redžovic, Petar Vukelić, Danijela Veljković, Tamara Gulić, Herman Haller i Daniel Rukavina. "Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy." American Journal of Reproductive Immunology 64 (2010): 347-358. https://doi.org/10.1111/j.1600-0897.2010.00844.x

Laškarin, G., et al. (2010) 'Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy', American Journal of Reproductive Immunology, 64, str. 347-358. doi: 10.1111/j.1600-0897.2010.00844.x

Laškarin G, Redžovic A, Vukelić P, Veljković D, Gulić T, Haller H, i sur.. Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy. American Journal of Reproductive Immunology [Internet]. 04.2010. [pristupljeno 13.11.2024.];64:347-358. doi: 10.1111/j.1600-0897.2010.00844.x

G. Laškarin, et al., "Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy", American Journal of Reproductive Immunology, vol. 64, str. 347-358, Travanj 2010. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:880108. [Citirano: 13.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:880108
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Podaci o radu
Naslov (engleski)Phenotype of NK Cells and Cytotoxic/Apoptotic Mediators Expression in Ectopic Pregnancy
AutorGordana Laškarin
AutorArnela Redžovic
AutorPetar Vukelić
AutorDanijela Veljković
AutorTamara Gulić
AutorHerman Haller
AutorDaniel Rukavina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Imunologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Ginekologija i opstetricija
Sažetak (engleski)
Phenotype of NK cells and cytotoxic/apoptotic mediators expression in ectopic pregnancy. Am J Reprod Immunol 2010 Problem The expression of cytotoxic/apoptotic mediators and the phenotype characteristics of uterine NK cells (uNK) in tubal ectopic pregnancy (EP) were investigated. Method of study Samples of uterine decidua and tubal mucosa as well as peripheral blood (PB) of the same women with EP were used for phenotype characterization of NK cells and detection of cytotoxic/apoptotic mediators and IL-15. Results In tubal mucosa, perforin, FasL, granulysin and IL-15 were almost completely absent, but they were present in normal and EP uterine deciduas. TRAIL was present on trophoblast and tubal mucosa, contrary to its lack in normal and EP uterine decidua. CD16-CD56dim NK cells, mostly CD94- and NKG2A-, predominate in tubal mucosa, whereas CD16-CD56bright NK cells, predominantly CD94+ and NKG2A+ prevail in EP uterine decidua. NK cells at the EP implantation site express lower percentages of perforin and granulysin, but they express a higher percentage of TRAIL than do EP uterine decidual and PB NK cells. Lower percentage of TNF-α-expressing and IL-4-expressing NK cells were found at the implantation site compared to EP uterine decidua. Conclusions Authentic uNK cell population seems to be insufficient to restrict trophoblast invasion because of low expression of cytotoxic/apoptotic mediators.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaAmerican Journal of Reproductive Immunology
Brojčani podacivol. 64, str. 347-358
p-ISSN1046-7408
e-ISSN1600-0897
DOIhttps://doi.org/10.1111/j.1600-0897.2010.00844.x
URN:NBNurn:nbn:hr:184:880108
Datum objave publikacije2010-04
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1111/j.1600-0897.2010.00844.x
Vrsta resursaTekst
Prava pristupaOgraničen pristup
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Datum i vrijeme pohrane2023-06-30 08:59:23