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Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications
Journal of Cardiovascular Development and Disease, 10 (2023), 5; 213. https://doi.org/10.3390/jcdd10050213
Knežević, Danijel; Ćurko-Cofek, Božena; Batinac, Tanja; Laškarin, Gordana; Rakić, Marijana; Šoštarič, Maja; Zdravković, Marko; Šustić, Alan; Sotošek, Vlatka; Batičić, Lara

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Knežević, D., Ćurko Cofek, B., Batinac, T., Laškarin, G., Rakić, M., Šoštarič, M. ... Batičić, L. (2023). Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications. Journal of Cardiovascular Development and Disease, 10. (5). doi: 10.3390/jcdd10050213

Knežević, Danijel, et al. "Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications." Journal of Cardiovascular Development and Disease, vol. 10, br. 5, 2023. https://doi.org/10.3390/jcdd10050213

Knežević, Danijel, Božena Ćurko Cofek, Tanja Batinac, Gordana Laškarin, Marijana Rakić, Maja Šoštarič, Marko Zdravković, Alan Šustić, Vlatka Sotošek i Lara Batičić. "Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications." Journal of Cardiovascular Development and Disease 10, br. 5 (2023). https://doi.org/10.3390/jcdd10050213

Knežević, D., et al. (2023) 'Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications', Journal of Cardiovascular Development and Disease, 10(5). doi: 10.3390/jcdd10050213

Knežević D, Ćurko Cofek B, Batinac T, Laškarin G, Rakić M, Šoštarič M, i sur.. Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications. Journal of Cardiovascular Development and Disease [Internet]. 13.05.2023. [pristupljeno 04.12.2024.];10(5). doi: 10.3390/jcdd10050213

D. Knežević, et al., "Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications", Journal of Cardiovascular Development and Disease, vol. 10, br. 5, Svibanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:475688. [Citirano: 04.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:475688
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Podaci o radu
Naslov (engleski)Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications
AutorDanijel Knežević
AutorBožena Ćurko-Cofek
AutorTanja Batinac
AutorGordana Laškarin
AutorMarijana Rakić
AutorMaja Šoštarič
AutorMarko Zdravković
AutorAlan Šustić
AutorVlatka Sotošek
AutorLara Batičić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za dermatovenerologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Anesteziologija i reanimatologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Kirurgija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
Cardiac surgery is one of the highest-risk procedures, usually involving cardiopulmonary bypass and commonly inducing endothelial injury that contributes to the development of perioperative and postoperative organ dysfunction. Substantial scientific efforts are being made to unravel the complex interaction of biomolecules involved in endothelial dysfunction to find new therapeutic targets and biomarkers and to develop therapeutic strategies to protect and restore the endothelium. This review highlights the current state-of-the-art knowledge on the structure and function of the endothelial glycocalyx and mechanisms of endothelial glycocalyx shedding in cardiac surgery. Particular emphasis is placed on potential strategies to protect and restore the endothelial glycocalyx in cardiac surgery. In addition, we have summarized and elaborated the latest evidence on conventional and potential biomarkers of endothelial dysfunction to provide a comprehensive synthesis of crucial mechanisms of endothelial dysfunction in patients undergoing cardiac surgery, and to highlight their clinical implications.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Cardiovascular Development and Disease
Brojčani podacivol. 10, br. 5, 213
e-ISSN2308-3425
DOIhttps://doi.org/10.3390/jcdd10050213
URN:NBNurn:nbn:hr:184:475688
Datum objave publikacije2023-05-13
ProjektŠifra: uniri-biomed-18-40
Naziv (hrvatski): Karakterizacija endotelne disfunkcije i uloga IL-18 u razvoju ishemijsko reperfuzijske ozljede nakon kirurške revaskularizacije miokarda
Pravna nadležnost: Hrvatska
Financijer: Sveučilište u Rijeci
URL dokumentahttps://www.mdpi.com/2308-3425/10/5/213
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-05-19 06:46:03