prikaz prve stranice dokumenta A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy
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A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy
European Archives of Oto-Rhino-Laryngology, 280 (2022), 3; 1381-1390. https://doi.org/10.1007/s00405-022-07668-1
Grasl, Stefan; Frommlet, Florian; Faisal, Muhammad; Marijić, Blažen; Schmid, Elisabeth; Heiduschka, Gregor; Brunner, Markus; Grasl, Matthaeus C.; Erovic, Boban M.; Janik, Stefan

Citirajte ovaj rad

Grasl, S., Frommlet, F., Faisal, M., Marijić, B., Schmid, E., Heiduschka, G. ... Janik, S. (2022). A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy. European Archives of Oto-Rhino-Laryngology, 280. (3), 1381-1390. doi: 10.1007/s00405-022-07668-1

Grasl, Stefan, et al. "A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy." European Archives of Oto-Rhino-Laryngology, vol. 280, br. 3, 2022, str. 1381-1390. https://doi.org/10.1007/s00405-022-07668-1

Grasl, Stefan, Florian Frommlet, Muhammad Faisal, Blažen Marijić, Elisabeth Schmid, Gregor Heiduschka, Markus Brunner, Matthaeus C. Grasl, Boban M. Erovic i Stefan Janik. "A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy." European Archives of Oto-Rhino-Laryngology 280, br. 3 (2022): 1381-1390. https://doi.org/10.1007/s00405-022-07668-1

Grasl, S., et al. (2022) 'A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy', European Archives of Oto-Rhino-Laryngology, 280(3), str. 1381-1390. doi: 10.1007/s00405-022-07668-1

Grasl S, Frommlet F, Faisal M, Marijić B, Schmid E, Heiduschka G, i sur.. A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy. European Archives of Oto-Rhino-Laryngology [Internet]. 01.10.2022. [pristupljeno 05.12.2024.];280(3):1381-1390. doi: 10.1007/s00405-022-07668-1

S. Grasl, et al., "A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy", European Archives of Oto-Rhino-Laryngology, vol. 280, br. 3, str. 1381-1390, Listopad 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:413136. [Citirano: 05.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:413136
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Naslov (engleski)A new nomogram to predict oncological outcome in laryngeal and hypopharyngeal carcinoma patients after laryngopharyngectomy
AutorStefan Grasl
AutorFlorian Frommlet
AutorMuhammad Faisal
AutorBlažen Marijić
AutorElisabeth Schmid
AutorGregor Heiduschka
AutorMarkus Brunner
AutorMatthaeus C. Grasl
AutorBoban M. Erovic
AutorStefan Janik
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za otorinolaringologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Otorinolaringologija
Sažetak (engleski)
Abstract Background: To create nomograms for better prediction of the oncological outcome in advanced laryngeal (LxCAs) or hypopharyngeal (HpxCAs) cancer after laryngopharyngectomy. Materials: 239 patients who underwent total laryngectomy or laryngopharyngectomy due to LxCA (52.7%) or HpxCA (47.3%) were included in this study. Based on clinical risk factors (tumor site, lymph node involvement, salvage setting), we created nomograms for prediction of disease-specific survival (DSS) and disease-free survival (DFS). Results: HpxCAs showed a higher rate of lymph node involvement (p < 0.001), a 2.47-fold higher risk of a 2nd head and neck cancer (p = 0.009) and significantly worse loco-regional control rates (p = 0.003) compared to LxCAs. Positive neck nodes and salvage procedures were associated with significantly worse outcome. Nomograms demonstrated that hypopharyngeal tumors with positive neck nodes in salvage situations had the worst oncological outcome with a 5-year DSS of 15-20%. Conclusions: The oncological outcome is worse in hypopharyngeal carcinomas and could be easily quantified by our nomograms that are based on tumor site, lymph node involvement and salvage situation.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaEuropean Archives of Oto-Rhino-Laryngology
Brojčani podacivol. 280, br. 3, str. 1381-1390
p-ISSN0937-4477
e-ISSN1434-4726
DOIhttps://doi.org/10.1007/s00405-022-07668-1
URN:NBNurn:nbn:hr:184:413136
Datum objave publikacije2022-10-01
URL dokumentahttps://link.springer.com/10.1007/s00405-022-07668-1
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-05-17 08:20:46