COVID-19 is a multisystem disease that, although predominantly affecting the respiratory system, can affect almost any organ system and requires structured rehabilitation of a multidisciplinary team. Acute, early, rehabilitation during the first 30 days of infection constitutes only the first phase of rehabilitation of persons with COVID-19. Symptoms and signs of physical, neurocognitive, and psychological consequences after SARS-CoV2 infection may persist for weeks or months after the end of the acute phase of the disease, and may develop in individuals who have a mild clinical picture and have not been hospitalized. The most common symptoms and signs that occur after the acute phase of COVID-19 are fatigue, shortness of breath, cough, joint and muscle pain, and insomnia and increased hair effluvium. Patients whose clinical condition in the acute phase of the disease required treatment with mechanical ventilation may have long-term consequences, including physical weakness and neurocognitive dysfunction (brain fog) characterized by loss of intellectual functions such as concentration and short-term memory. Patients with cognitive dysfunction have problems with word recollection, dyscalculia, and concentration. The PostCOVID Day Hospital for Physical Medicine and Rehabilitation rehabilitation program is implemented by a multidisciplinary team focused on the overall functioning of patients, not just the treated organ or organ system, including the consequences of COVID-19 disease, possible treatment complications and comorbidities. The goal of rehabilitation of patients in the post-acute COVID-19 period is to achieve complete functional recovery and adequate quality of life.