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Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study
Biomedicines, 10 (2022), 9; 2175. https://doi.org/10.3390/biomedicines10092175
Lekšić, Gloria; Baretić, Maja; Gudelj, Lara; Radić, Marija; Miličić, Iva; Ivanišević, Marina; Jurišić Eržen, Dubravka

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Lekšić, G., Baretić, M., Gudelj, L., Radić, M., Miličić, I., Ivanišević, M. i Jurišić Eržen, D. (2022). Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study. Biomedicines, 10. (9). doi: 10.3390/biomedicines10092175

Lekšić, Gloria, et al. "Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study." Biomedicines, vol. 10, br. 9, 2022. https://doi.org/10.3390/biomedicines10092175

Lekšić, Gloria, Maja Baretić, Lara Gudelj, Marija Radić, Iva Miličić, Marina Ivanišević i Dubravka Jurišić Eržen. "Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study." Biomedicines 10, br. 9 (2022). https://doi.org/10.3390/biomedicines10092175

Lekšić, G., et al. (2022) 'Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study', Biomedicines, 10(9). doi: 10.3390/biomedicines10092175

Lekšić G, Baretić M, Gudelj L, Radić M, Miličić I, Ivanišević M, i sur.. Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study. Biomedicines [Internet]. 02.09.2022. [pristupljeno 05.05.2024.];10(9). doi: 10.3390/biomedicines10092175

G. Lekšić, et al., "Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study", Biomedicines, vol. 10, br. 9, Rujan 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:337509. [Citirano: 05.05.2024.]

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Naslov (engleski)Glycemic Variability in Type 1 Diabetes Mellitus Pregnancies—Novel Parameters in Predicting Large-for-Gestational-Age Neonates: A Prospective Cohort Study
AutorGloria Lekšić
AutorMaja Baretić
AutorLara Gudelj
AutorMarija Radić
AutorIva Miličić
AutorMarina Ivanišević
AutorDubravka Jurišić Eržen
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Pregnancies with type 1 diabetes mellitus (T1DM) have a high incidence of large-for-gestational-age neonates (LGA) despite optimal glycemic control. In recent years, glycemic variability (GV) has emerged as a possible risk factor for LGA, but the results of the conducted studies are unclear. This study analyzed the association between GV and LGA development in pregnancies with T1DM. This was a prospective cohort study of patients with T1DM who used continuous glucose monitoring (CGM) during pregnancy. Patients were followed from the first trimester to birth. GV parameters were calculated for every trimester using the EasyGV calculator. The main outcomes were LGA or no-LGA. Logistic regression analysis was used to assess the association between GV parameters and LGA. In total, 66 patients were included. The incidence of LGA was 36%. The analysis extracted several GV parameters that were significantly associated with the risk of LGA. The J-index was the only significant parameter in every trimester of pregnancy (odds ratios with confidence intervals were 1.33 (1.02, 1.73), 3.18 (1.12, 9.07), and 1.37 (1.03, 1.82), respectively. Increased GV is a risk factor for development of LGA. The J-index is a possible novel GV parameter that may be assessed in all three trimesters of pregnancy together with glycated hemoglobin and time-in-range.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomedicines
Brojčani podacivol. 10, br. 9, 2175
e-ISSN2227-9059
DOIhttps://doi.org/10.3390/biomedicines10092175
URN:NBNurn:nbn:hr:184:337509
Datum objave publikacije2022-09-02
URL dokumentahttps://www.mdpi.com/2227-9059/10/9/2175
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-09-15 07:55:27