prikaz prve stranice dokumenta Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro
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Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro
International Journal of Environmental Research and Public Health, 19 (2022), 10; 6177. https://doi.org/10.3390/ijerph19106177
Piletić, Kaća; Kovač, Bruno; Perčić, Marko; Žigon, Jure; Broznić, Dalibor; Karleuša, Ljerka; Lučić Blagojević, Sanja; Oder, Martina; Gobin, Ivana

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Piletić, K., Kovač, B., Perčić, M., Žigon, J., Broznić, D., Karleuša, Lj. ... Gobin, I. (2022). Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro. International Journal of Environmental Research and Public Health, 19. (10). doi: 10.3390/ijerph19106177

Piletić, Kaća, et al. "Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro." International Journal of Environmental Research and Public Health, vol. 19, br. 10, 2022. https://doi.org/10.3390/ijerph19106177

Piletić, Kaća, Bruno Kovač, Marko Perčić, Jure Žigon, Dalibor Broznić, Ljerka Karleuša, Sanja Lučić Blagojević, Martina Oder i Ivana Gobin. "Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro." International Journal of Environmental Research and Public Health 19, br. 10 (2022). https://doi.org/10.3390/ijerph19106177

Piletić, K., et al. (2022) 'Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro', International Journal of Environmental Research and Public Health, 19(10). doi: 10.3390/ijerph19106177

Piletić K, Kovač B, Perčić M, Žigon J, Broznić D, Karleuša Lj, i sur.. Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro. International Journal of Environmental Research and Public Health [Internet]. 2022. [pristupljeno 17.04.2024.];19(10). doi: 10.3390/ijerph19106177

K. Piletić, et al., "Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro", International Journal of Environmental Research and Public Health, vol. 19, br. 10, 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:346825. [Citirano: 17.04.2024.]

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Podaci o radu
Naslov (engleski)Disinfecting Action of Gaseous Ozone on OXA-48- Producing Klebsiella pneumoniae Biofilm In Vitro
AutorKaća Piletić
AutorBruno Kovač
AutorMarko Perčić
MBZ: 353085
AutorJure Žigon
AutorDalibor Broznić
MBZ: 270072
AutorLjerka Karleuša
MBZ: 334545
AutorSanja Lučić Blagojević
MBZ: 186655
AutorMartina Oder
AutorIvana Gobin
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Klebsiella pneumoniae is an emerging multidrug- resistant pathogen that can contaminate hospital surfaces in the form of a biofilm which is hard to remove with standard disinfectants. Because of biofilm resistance to conservative disinfectants, the application of new disinfection technologies is becoming more frequent. Ozone gas has antimicrobial activity but there is lack of data on its action against K. pneumoniae biofilm. The aim of this study was to investigate the effects and mechanisms of action of gaseous ozone on the OXA-48-procuding K. pneumoniae biofilm. A 24 h biofilm of K. pneumoniae formed on ceramic tiles was subsequently exposed to different concentrations of ozone during one and two hours to determine the optimal ozone concentration. Afterwards, the total bacteria count, total biomass and oxidative stress levels were monitored. A total of 25 ppm of gaseous ozone was determined to be optimal ozone concentration and caused reduction in total bacteria number in all strains of K. pneumoniae for 2.0 log10 CFU/cm2, followed by reduction in total biomass up to 88.15%. Reactive oxygen species levels significantly increased after the ozone treatment at 182% for the representative K. pneumoniae NCTC 13442 strain. Ozone gas in the concentration of 25 ppm caused significant biofilm reduction but did not completely eradicate the K. pneumoniae biofilm formed on ceramics. In conclusion, ozone gas has great potential to be used as an additional hygiene measure in joint combat against biofilm in hospital environments.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Environmental Research and Public Health
Brojčani podacivol. 19, br. 10, 6177
p-ISSN1660-4601
DOIhttps://doi.org/10.3390/ijerph19106177
URN:NBNurn:nbn:hr:184:346825
Datum objave publikacije2022
URL dokumentahttp://bib.irb.hr/1197491
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-06-29 09:38:01