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Cytokines in Patients with Lung Cancer
Scandinavian Journal of Immunology, 57 (2003), 2; 173-178. https://doi.org/10.1046/j.1365-3083.2003.01205.x
Matanić, Dubravka.; Beg-Zec, Zlata; Stojanović, D.; Matakorić, N.; Flego, Veljko; Milevoj-Ribić, F.

Citirajte ovaj rad

Matanić, D., Beg Zec, Z., Stojanović, D., Matakorić, N., Flego, V. i Milevoj Ribić, F. (2003). Cytokines in Patients with Lung Cancer. Scandinavian Journal of Immunology, 57. (2), 173-178. doi: 10.1046/j.1365-3083.2003.01205.x

Matanić, Dubravka., et al. "Cytokines in Patients with Lung Cancer." Scandinavian Journal of Immunology, vol. 57, br. 2, 2003, str. 173-178. https://doi.org/10.1046/j.1365-3083.2003.01205.x

Matanić, Dubravka., Zlata Beg Zec, D. Stojanović, N. Matakorić, Veljko Flego i F. Milevoj Ribić. "Cytokines in Patients with Lung Cancer." Scandinavian Journal of Immunology 57, br. 2 (2003): 173-178. https://doi.org/10.1046/j.1365-3083.2003.01205.x

Matanić, D., et al. (2003) 'Cytokines in Patients with Lung Cancer', Scandinavian Journal of Immunology, 57(2), str. 173-178. doi: 10.1046/j.1365-3083.2003.01205.x

Matanić D, Beg Zec Z, Stojanović D, Matakorić N, Flego V, Milevoj Ribić F. Cytokines in Patients with Lung Cancer. Scandinavian Journal of Immunology [Internet]. 02.2003. [pristupljeno 06.05.2024.];57(2):173-178. doi: 10.1046/j.1365-3083.2003.01205.x

D. Matanić, Z. Beg Zec, D. Stojanović, N. Matakorić, V. Flego i F. Milevoj Ribić, "Cytokines in Patients with Lung Cancer", Scandinavian Journal of Immunology, vol. 57, br. 2, str. 173-178, Veljača 2003. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:880908. [Citirano: 06.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:880908
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Podaci o radu
Naslov (engleski)Cytokines in Patients with Lung Cancer
AutorDubravka. Matanić
AutorZlata Beg-Zec
AutorD. Stojanović
AutorN. Matakorić
AutorVeljko Flego
AutorF. Milevoj-Ribić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Lung cancer is one of the most common malignant diseases and is amongst the leading causes of death. Cell-mediated immune response and cytokines could play an important role in antitumour immunity. The aim of the study was to evaluate the cytokines', tumour necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta) and IL-6, releasing capacity in patients with lung carcinoma and benign lung disease. A group of 41 patients were tested for the production of TNF-alpha, IL-1beta and IL-6 in bronchoalveolar lavage (BAL) and blood. The levels of cytokines in the lung cancer patients were: (1) in BAL - IL-6, 173 +/- 85 pg/ml; TNF-alpha, 170 +/- 116 pg/ml; and IL-1beta, 473 +/- 440 pg/ml; (2) in the blood - IL-6, 197 +/- 53 pg/ml; TNF-alpha, 311 +/- 202 pg/ml; and IL-1beta, 915 +/- 239 pg/ml. Alveolar macrophages of the patients with a lung cancer secreted significantly more cytokines, IL-6 (P = 0.0004) and IL-1beta (P = 0.0047), than alveolar macrophages of the patients with a nonmalignant lung cancer. However, significantly lower levels of cytokine production by the BAL cells were found in patients with small cell lung cancer. This production decreased further in phase IV of nonsmall cell lung cancer.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaScandinavian Journal of Immunology
Brojčani podacivol. 57, br. 2, str. 173-178
p-ISSN0300-9475
e-ISSN1365-3083
DOIhttps://doi.org/10.1046/j.1365-3083.2003.01205.x
URN:NBNurn:nbn:hr:184:880908
Datum objave publikacije2003-02
URL dokumentahttp://doi.wiley.com/10.1046/j.1365-3083.2003.01205.x
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-03-17 22:16:25