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Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.
Cellular physiology and biochemistry, 42 (2017), 6; 2318-2329. https://doi.org/10.1159/000480004
Šućurović, Sandra; Nikolić, Tamara; Brosens, J. Jan; Mulac-Jeričević, Biserka

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Šućurović, S., Nikolić, T., Brosens, J. J. i Mulac Jeričević, B. (2017). Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.. Cellular physiology and biochemistry, 42. (6), 2318-2329. doi: 10.1159/000480004

Šućurović, Sandra, et al. "Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.." Cellular physiology and biochemistry, vol. 42, br. 6, 2017, str. 2318-2329. https://doi.org/10.1159/000480004

Šućurović, Sandra, Tamara Nikolić, J. Jan Brosens i Biserka Mulac Jeričević. "Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.." Cellular physiology and biochemistry 42, br. 6 (2017): 2318-2329. https://doi.org/10.1159/000480004

Šućurović, S., et al. (2017) 'Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.', Cellular physiology and biochemistry, 42(6), str. 2318-2329. doi: 10.1159/000480004

Šućurović S, Nikolić T, Brosens JJ, Mulac Jeričević B. Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.. Cellular physiology and biochemistry [Internet]. 2017. [pristupljeno 26.04.2024.];42(6):2318-2329. doi: 10.1159/000480004

S. Šućurović, T. Nikolić, J. J. Brosens i B. Mulac Jeričević, "Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.", Cellular physiology and biochemistry, vol. 42, br. 6, str. 2318-2329, 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:416742. [Citirano: 26.04.2024.]

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Naslov (engleski)Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy.
AutorSandra Šućurović
AutorTamara Nikolić
AutorJ. Jan Brosens
AutorBiserka Mulac-Jeričević
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Fiziologija čovjeka
Sažetak (engleski)
BACKGROUND: Fibroblast growth factors (FGFs), in complex with their receptors (FGFRs), regulate a broad spectrum of biological functions including cellular proliferation, survival, migration, and differentiation. In human endometrial stromal cells, FGF9 is regulated with estrogen (E). METHODS/RESULTS: First, we report that in uterus tissue of ovariectomized wild type mice, FGF9 is present in three isoforms and is regulated with E. Second, we found that during peri-implantation, Fgf9 expression reached its peak at day 4.5 of pregnancy. Immunofluorescence analyses demonstrated overlapping FGF9 and COX2 expression surrounding the blastocyst attachment site. Next, we identified FGF9- and CD31-positive cells as a part of the microvessels ; however, expression was localized to a distinct population of cells. Finally, our data showed synchronized, spatial expression of FGF9 on the luminal epithelium with FGFR2 present on the trophectoderm. CONCLUSION: Our data suggest that FGF9 is a crucial factor required to establish the appropriate microenvironment for successful implantation and the maintenance of pregnancy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCellular physiology and biochemistry
Brojčani podacivol. 42, br. 6, str. 2318-2329
p-ISSN1015-8987
DOIhttps://doi.org/10.1159/000480004
URN:NBNurn:nbn:hr:184:416742
Datum objave publikacije2017
ProjektŠifra: 13.06.1.1.08
Naziv (hrvatski): Uloga progesterona u reproduktivnim i nereproduktivnim organima
Voditelj: Biserka Mulac-Jeričević
Pravna nadležnost: Hrvatska
Financijer: NadSve
Linija financiranja: Sveučilište u Rijeci
URL dokumentahttp://bib.irb.hr/957688
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2022-03-09 11:37:37