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Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism
Environmental Research, 152 (2017); 375-385. https://doi.org/10.1016/j.envres.2016.08.035
Snoj Tratnik, Janja; Falnoga, Ingrid; Trdin, Ajda; Mazej, Darja; Fajon, Vesna; Miklavčič, Ana; Kobal, Alfred; Osredkar, Joško; Sešek Briški, Alenka; Krsnik, Mladen; Neubauer, David; Kodrič, Jana; Stropnik, Staša; Gosar, David; Lešnik Musek, Petra; Marc, Janja; Jurkovič Mlakar, Simona; Petrović, Oleg; Vlašić- Cicvarić, Inge; Prpić, Igor; Milardović, Ana; Radić Nišević, Jelena; Vuković, Danijela; Fišić, Elizabeta; Špirić, Zdravko; Horvat, Milena Više autora...

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Snoj Tratnik, J., Falnoga, I., Trdin, A., Mazej, D., Fajon, V., Miklavčič, A. ... Horvat, M. (2017). Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism. Environmental Research, 152., 375-385. doi: 10.1016/j.envres.2016.08.035

Snoj Tratnik, Janja, et al. "Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism." Environmental Research, vol. 152, 2017, str. 375-385. https://doi.org/10.1016/j.envres.2016.08.035

Snoj Tratnik, Janja, Ingrid Falnoga, Ajda Trdin, Darja Mazej, Vesna Fajon, Ana Miklavčič, Alfred Kobal, et al. "Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism." Environmental Research 152 (2017): 375-385. https://doi.org/10.1016/j.envres.2016.08.035

Snoj Tratnik, J., et al. (2017) 'Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism', Environmental Research, 152, str. 375-385. doi: 10.1016/j.envres.2016.08.035

Snoj Tratnik J, Falnoga I, Trdin A, Mazej D, Fajon V, Miklavčič A, i sur.. Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism. Environmental Research [Internet]. 2017. [pristupljeno 04.12.2024.];152:375-385. doi: 10.1016/j.envres.2016.08.035

J. Snoj Tratnik, et al., "Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism", Environmental Research, vol. 152, str. 375-385, 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:939845. [Citirano: 04.12.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:939845
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Podaci o radu
Naslov (engleski)Prenatal mercury exposure, neurodevelopment and apolipoprotein E genetic polymorphism
AutorJanja Snoj Tratnik
AutorIngrid Falnoga
AutorAjda Trdin
AutorDarja Mazej
AutorVesna Fajon
AutorAna Miklavčič
AutorAlfred Kobal
AutorJoško Osredkar
AutorAlenka Sešek Briški
AutorMladen Krsnik
AutorDavid Neubauer
AutorJana Kodrič
AutorStaša Stropnik
AutorDavid Gosar
AutorPetra Lešnik Musek
AutorJanja Marc
AutorSimona Jurkovič Mlakar
AutorOleg Petrović
AutorInge Vlašić- Cicvarić
AutorIgor Prpić
AutorAna Milardović
AutorJelena Radić Nišević
AutorDanijela Vuković
AutorElizabeta Fišić
MBZ: 253916
AutorZdravko Špirić
AutorMilena Horvat
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za ginekologiju i opstetriciju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za pedijatriju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za zdravstvenu ekologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Javno zdravstvo i zdravstvena zaštita
Zdravstvena ekologija
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Pedijatrija
Sažetak (engleski)
The aim of the present study was to evaluate the association between prenatal exposure to mercury (Hg) and neurodevelopment of the child, taking into account genetic polymorphism of apolipoprotein E (Apoe) and other relevant confounders. Six hundred and one mother-child pairs were recruited from the central Slovenia region and 243 from Rijeka, on the Croatian coast of the northern Adriatic. The total Hg in cord blood, Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) assessment at 18 months of age and Apoe genotyping was performed on 361 children ; 237 of them were from Slovenia and 124 from Croatia. The results showed negative association between low- to-moderate Hg exposure in children with normal neurodevelopmental outcome and cognitive and fine motor scores at 18 months of age as assessed by BayleyIII. The Hg-related decrease in cognitive score was observed only in children carrying atleastone Apoe ε4 allele, while the decrease in fine motor scores was independent of the Apoe genotype. Adjusting for selenium (Se) and lead (Pb) levels, a positive association between Se and the language score and a negative association between Pb and the motor score was observed, but not in the subgroup of children carrying the ε4 allele.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeRukopis poslan na recenzijski postupak (preprint)
Naslov časopisaEnvironmental Research
Brojčani podacivol. 152, str. 375-385
p-ISSN0013-9351
DOIhttps://doi.org/10.1016/j.envres.2016.08.035
URN:NBNurn:nbn:hr:184:939845
Datum objave publikacije2017
URL dokumentahttp://bib.irb.hr/846946
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2022-03-03 18:31:14