prikaz prve stranice dokumenta Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.
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Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.
International Journal of Pharmacy Practice., 26 (2018), 2; 156-164. https://doi.org/10.1111/ijpp.12383
Van Heerden, JA; Burger, JR; Gerber, JJ; Vlahović‐ Palčevski, Vera.

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Van Heerden, J., Burger, J., Gerber, J. i Vlahović‐ Palčevski, V. (2018). Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.. International Journal of Pharmacy Practice., 26. (2), 156-164. doi: 10.1111/ijpp.12383

Van Heerden, JA, et al. "Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.." International Journal of Pharmacy Practice., vol. 26, br. 2, 2018, str. 156-164. https://doi.org/10.1111/ijpp.12383

Van Heerden, JA, JR Burger, JJ Gerber i Vera. Vlahović‐ Palčevski. "Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.." International Journal of Pharmacy Practice. 26, br. 2 (2018): 156-164. https://doi.org/10.1111/ijpp.12383

Van Heerden, J., et al. (2018) 'Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.', International Journal of Pharmacy Practice., 26(2), str. 156-164. doi: 10.1111/ijpp.12383

Van Heerden J, Burger J, Gerber J, Vlahović‐ Palčevski V. Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.. International Journal of Pharmacy Practice. [Internet]. 2018. [pristupljeno 19.11.2024.];26(2):156-164. doi: 10.1111/ijpp.12383

J. Van Heerden, J. Burger, J. Gerber i V. Vlahović‐ Palčevski, "Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.", International Journal of Pharmacy Practice., vol. 26, br. 2, str. 156-164, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:724298. [Citirano: 19.11.2024.]

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Naslov (engleski)Prevalence of potentially serious drug–drug interactions among South African elderly private health sector patients using the Mimica Matanović/Vlahović‐Palčevski protocol.
Naslov (engleski)International Journal of Pharmacy Practice. 2018 Apr ; 26(2):156-64.
AutorJA Van Heerden
AutorJR Burger
AutorJJ Gerber
AutorVera. Vlahović‐ Palčevski
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za farmakologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Sažetak (engleski)
Objectives To determine the prevalence of potentially serious drug–drug interactions (DDIs) and their relationship with gender and age, among elderly in South Africa. Methods A cross‐sectional study was conducted using pharmaceutical claims data for 2013, for a total of 103 420 medical scheme beneficiaries’ ≥65 years. All medications dispensed within one calendar month where the days’ supply of medication dispensed overlapped, were grouped as one prescription. DDIs per prescription were then identified using the Mimica Matanović/Vlahović‐Palčevski DDI protocol. Results were interpreted using effect sizes, that is Cramér's V, Cohen's d and Cohen's ƒ2. Key findings A total of 331 659 DDIs were identified on 235 870 (25.8%, N = 912 713) prescriptions (mean 0.36 (SD 0.7) (95% CI, 0.36 to 0.37)). Women encountered 63.5% of all DDIs. Effect sizes for the association between DDIs and age group (Cramér's V = 0.06), and gender (Cramér's V = 0.05) was negligible. There was no difference between men and women regarding the mean number of DDIs identified per prescription (Cohen's d = 0.10). The number of medicine per prescription (ƒ2 = 0.51) was the biggest predictor of the DDIs. The most frequent interacting drug combinations were between central nervous system medicines (30.6%). Conclusion Our study is the first to report the prevalence of potentially serious DDIs among an elderly population in the South African private health sector utilising the Mimica Matanović/Vlahović‐ Palčevski DDI protocol. Overall, we identified DDIs in approximately 26% of the prescriptions in our study. Age and gender were not found to be predictors of potentially serious DDIs.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal of Pharmacy Practice.
Brojčani podacivol. 26, br. 2, str. 156-164
p-ISSN2042-7174
DOIhttps://doi.org/10.1111/ijpp.12383
URN:NBNurn:nbn:hr:184:724298
Datum objave publikacije2018
URL dokumentahttp://bib.irb.hr/1033399
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
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Datum i vrijeme pohrane2022-03-03 16:18:32