prikaz prve stranice dokumenta Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements
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Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements
Journal of Diabetes and its Complications, 34 (2020), 3; 1-7. https://doi.org/10.1016/j.jdiacomp.2019.107512
Mikolašević, Ivana; Lukenda Žanko, Vesna; Jakopčić, Ivan; Domislović, Viktor; Mijić, Ana; Stevanović, Tajana; Delija, Božena; Bokun, Tomislav; Dinjar Kujundžić, Petra; Ostojić, Ana; Filipec Kanižaj, Tajana; Grgurević, Ivica; Krznarić, Željko.; Štimac, Davor; Targher, G. Više autora...

Citirajte ovaj rad

Mikolašević, I., Lukenda Žanko, V., Jakopčić, I., Domislović, V., Mijić, A., Stevanović, T. ... Targher, G. (2020). Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements. Journal of Diabetes and its Complications, 34. (3), 1-7. doi: 10.1016/j.jdiacomp.2019.107512

Mikolašević, Ivana, et al. "Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements." Journal of Diabetes and its Complications, vol. 34, br. 3, 2020, str. 1-7. https://doi.org/10.1016/j.jdiacomp.2019.107512

Mikolašević, Ivana, Vesna Lukenda Žanko, Ivan Jakopčić, Viktor Domislović, Ana Mijić, Tajana Stevanović, Božena Delija, et al. "Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements." Journal of Diabetes and its Complications 34, br. 3 (2020): 1-7. https://doi.org/10.1016/j.jdiacomp.2019.107512

Mikolašević, I., et al. (2020) 'Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements', Journal of Diabetes and its Complications, 34(3), str. 1-7. doi: 10.1016/j.jdiacomp.2019.107512

Mikolašević I, Lukenda Žanko V, Jakopčić I, Domislović V, Mijić A, Stevanović T, i sur.. Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements. Journal of Diabetes and its Complications [Internet]. 03.2020. [pristupljeno 13.11.2024.];34(3):1-7. doi: 10.1016/j.jdiacomp.2019.107512

I. Mikolašević, et al., "Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements", Journal of Diabetes and its Complications, vol. 34, br. 3, str. 1-7, Ožujak 2020. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:263812. [Citirano: 13.11.2024.]

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Podaci o radu
Naslov (engleski)Prospective evaluation of non-alcoholic fatty liver disease by elastographic methods of liver steatosis and fibrosis; controlled attenuation parameter and liver stiffness measurements
AutorIvana Mikolašević
AutorVesna Lukenda Žanko
AutorIvan Jakopčić
AutorViktor Domislović
AutorAna Mijić
AutorTajana Stevanović
AutorBožena Delija
AutorTomislav Bokun
AutorPetra Dinjar Kujundžić
AutorAna Ostojić
AutorTajana Filipec Kanižaj
AutorIvica Grgurević
AutorŽeljko. Krznarić
AutorDavor Štimac
AutorG. Targher
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Aims: To examine the temporal changes of both controlled attenuation parameter (CAP) and liver stiffness measurements (LSM), assessed by Fibroscan, in a large sample of patients with non-alcoholic fatty liver disease (NAFLD). Methods: In this prospective, observational study, we consecutively enrolled 507 adult individuals with Fibroscan-defined NAFLD who were followed for a mean period of 21.2 ± 11.7 months. Results: During the follow-up period, 84 patients (16.5%) had a progression of CAP of at least 20% with a median time of 39.93 months, while 201 (39.6%) patients had a progression of LSM of at least 20% with median time of 30.46 months. There were significant differences in the proportion of LSM progression across body mass index (BMI) categories, with obese patients having the highest risk of progression over the follow-up (hazard ratio 1.66; 95%CI 1.23-2.25). Multivariable regression analysis showed that BMI and serum creatinine levels were the strongest predictors for CAP progression in the whole population, while HOMA-estimated insulin resistance was an independent predictor of LSM progression over time in the subgroup of obese patients. Conclusion: This prospective study shows for the first time that the progression risk of both liver steatosis and fibrosis, detected non-invasively by Fibroscan, is relevant and shares essentially the same metabolic risk factors that are associated with NAFLD progression detected by other invasive methods.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Diabetes and its Complications
Brojčani podacivol. 34, br. 3, str. 1-7
p-ISSN1056-8727
DOIhttps://doi.org/10.1016/j.jdiacomp.2019.107512
URN:NBNurn:nbn:hr:184:263812
Datum objave publikacije2020-03
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S1056872719306348
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
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Datum i vrijeme pohrane2022-03-03 12:57:21