prikaz prve stranice dokumenta Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice
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Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice
Journal of Functional Foods, 23 (2016); 177-187. https://doi.org/10.1016/j.jff.2016.02.036
Giacometti, Jasminka; Muhvić, Damir; Pavletić, Adriano; Đudarić, Luka

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Giacometti, J., Muhvić, D., Pavletić, A. i Đudarić, L. (2016). Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice. Journal of Functional Foods, 23., 177-187. doi: 10.1016/j.jff.2016.02.036

Giacometti, Jasminka, et al. "Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice." Journal of Functional Foods, vol. 23, 2016, str. 177-187. https://doi.org/10.1016/j.jff.2016.02.036

Giacometti, Jasminka, Damir Muhvić, Adriano Pavletić i Luka Đudarić. "Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice." Journal of Functional Foods 23 (2016): 177-187. https://doi.org/10.1016/j.jff.2016.02.036

Giacometti, J., et al. (2016) 'Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice', Journal of Functional Foods, 23, str. 177-187. doi: 10.1016/j.jff.2016.02.036

Giacometti J, Muhvić D, Pavletić A, Đudarić L. Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice. Journal of Functional Foods [Internet]. 2016. [pristupljeno 07.05.2024.];23:177-187. doi: 10.1016/j.jff.2016.02.036

J. Giacometti, D. Muhvić, A. Pavletić i L. Đudarić, "Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice", Journal of Functional Foods, vol. 23, str. 177-187, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:183522. [Citirano: 07.05.2024.]

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Naslov (engleski)Cocoa polyphenols exhibit antioxidant, anti-inflammatory, anticancerogenic and anti-necrotic activity in carbon tetrachloride-intoxicated mice
AutorJasminka Giacometti
MBZ: 177203
AutorDamir Muhvić
AutorAdriano Pavletić
AutorLuka Đudarić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anatomiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Kemija
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Biologija
Sažetak (engleski)
The therapeutic effects of cocoa polyphenols on acute carbon tetrachloride (CCl4) -intoxicated mice were investigated. After determination polyphenols profile in the cocoa extract (CE), CE at a dose of 34.5 mg/kg and epicatechin (EC) at a dose of 2.24 mg/kg were intraperitoneally (i.p.) administered to BALB/cN mice following CCl4-treatment. CE and EC post-treatments suppressed hepatotoxicity and inflammation, ameliorated serum markers of liver injury, returned blood lactate and glucose levels to normal, stimulated synthesis and storage of liver glycogen, and modulated glucose metabolism imbalance induced by CCl4. Cocoa polyphenols also exhibited early stage antifibrotic and anticarcinogenic effects. They affected beneficially mitochondrial functionality acting on dysfunction in mitochondrial respiration caused by CCl4 and antioxidants regulation at subcellular levels.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Functional Foods
Brojčani podacivol. 23, str. 177-187
p-ISSN1756-4646
DOIhttps://doi.org/10.1016/j.jff.2016.02.036
URN:NBNurn:nbn:hr:184:183522
Datum objave publikacije2016
URL dokumentahttp://bib.irb.hr/796164
Vrsta resursaTekst
Prava pristupaZatvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-11 16:19:27