prikaz prve stranice dokumenta Activation of αSMA expressing perivascular cells during reactionary dentinogenesis
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Activation of αSMA expressing perivascular cells during reactionary dentinogenesis
International Endodontic Journal, 52 (2019), 1; 68-76. https://doi.org/10.1111/iej.12983
Vidovic-Zdrilic, Ivana; Vijaykumar, A.; Mina, M.

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Vidovic Zdrilic, I., Vijaykumar, A. i Mina, M. (2019). Activation of αSMA expressing perivascular cells during reactionary dentinogenesis. International Endodontic Journal, 52. (1), 68-76. doi: 10.1111/iej.12983

Vidovic Zdrilic, Ivana, et al. "Activation of αSMA expressing perivascular cells during reactionary dentinogenesis." International Endodontic Journal, vol. 52, br. 1, 2019, str. 68-76. https://doi.org/10.1111/iej.12983

Vidovic Zdrilic, Ivana, A. Vijaykumar i M. Mina. "Activation of αSMA expressing perivascular cells during reactionary dentinogenesis." International Endodontic Journal 52, br. 1 (2019): 68-76. https://doi.org/10.1111/iej.12983

Vidovic Zdrilic, I., Vijaykumar, A. i Mina, M. (2019) 'Activation of αSMA expressing perivascular cells during reactionary dentinogenesis', International Endodontic Journal, 52(1), str. 68-76. doi: 10.1111/iej.12983

Vidovic Zdrilic I, Vijaykumar A, Mina M. Activation of αSMA expressing perivascular cells during reactionary dentinogenesis. International Endodontic Journal [Internet]. 2019. [pristupljeno 11.11.2024.];52(1):68-76. doi: 10.1111/iej.12983

I. Vidovic Zdrilic, A. Vijaykumar i M. Mina, "Activation of αSMA expressing perivascular cells during reactionary dentinogenesis", International Endodontic Journal, vol. 52, br. 1, str. 68-76, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:447452. [Citirano: 11.11.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:447452
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Naslov (engleski)Activation of αSMA expressing perivascular cells during reactionary dentinogenesis
AutorIvana Vidovic-Zdrilic
AutorA. Vijaykumar
AutorM. Mina
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Sažetak (engleski)
Aim: To examine the contribution of perivascular cells expressing αSMA to reactionary dentinogenesis. Methodology: An inducible, Cre-loxP in vivo fate- mapping approach was used to examine the contribution of the descendants of cells expressing the αSMA-CreERT2 transgene to reactionary dentinogenesis in mice molars. Reactionary dentinogenesis was induced by experimental mild injury to dentine without pulp exposure. The Student's t test was used to determine statistical significance at *P ≤ 0.05. Results: The lineage tracing experiments revealed that mild injury to dentine first led to activation of αSMA-tdTomato+ cells in the entire pulp chamber. The percentage of areas occupied by αSMA-tdTomato+ in injured (7.5 ± 0.7%) teeth were significantly higher than in teeth without injury (2 ± 0.5%). After their activation, αSMA- tdTomato+ cells migrated towards the site of injury, gave rise to pulp cells and a few odontoblasts that became integrated into the existing odontoblast layer expressing Col2.3-GFP and Dspp. Conclusion: Mild insult to dentine activated perivascular αSMA-tdTomato+ cells giving rise to pulp cells as well as a few odontoblasts that were integrated into the pre-existing odontoblast layer.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Endodontic Journal
Brojčani podacivol. 52, br. 1, str. 68-76
p-ISSN0143-2885
DOIhttps://doi.org/10.1111/iej.12983
URN:NBNurn:nbn:hr:184:447452
Datum objave publikacije2019
URL dokumentahttp://bib.irb.hr/1048534
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-04 07:47:20